Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with all data for entry = 50015864
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
Ulsan National Institute of Science and Technology (UNIST)

Curated by ChEMBL
LigandPNGBDBM50186231((2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)ac...)
Affinity DataKi:  1.83E+5nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate assessed as inhibition constant by reciprocal analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
Ulsan National Institute of Science and Technology (UNIST)

Curated by ChEMBL
LigandPNGBDBM50220832(CHEMBL8211 | N-ethylmaleimide)
Affinity DataKi:  2.09E+5nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate assessed as inhibition constant by reciprocal analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
Ulsan National Institute of Science and Technology (UNIST)

Curated by ChEMBL
LigandPNGBDBM50186231((2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)ac...)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate incubated for 1 hr by multimode microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed