Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50015868
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590161BDBM50590161(CHEMBL5193408)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396018BDBM50396018(CHEMBL1230640)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590162BDBM50590162(CHEMBL5205660)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26106BDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in 5-methylcytosine oxidation by measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590161BDBM50590161(CHEMBL5193408)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in 5-methylcytosine oxidation preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590171BDBM50590171(CHEMBL5177215)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 47715BDBM47715(N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-o...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in 5-methylcytosine oxidation by measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590168BDBM50590168(CHEMBL5199439)
Affinity DataIC50: 8.66E+4nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590164BDBM50590164(CHEMBL5207325)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590163BDBM50590163(CHEMBL5198202)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590166BDBM50590166(CHEMBL5196825)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590165BDBM50590165(CHEMBL5194069)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590167BDBM50590167(CHEMBL5205573)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590170BDBM50590170(CHEMBL5198851)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590169BDBM50590169(CHEMBL5173988)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590172BDBM50590172(CHEMBL5183202)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590174BDBM50590174(CHEMBL5203367)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590173BDBM50590173(CHEMBL5195222)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590176BDBM50590176(CHEMBL5186458)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590175BDBM50590175(CHEMBL5169988)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590177BDBM50590177(CHEMBL5170671)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed