Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50019186
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616340(CHEMBL5435709)
Affinity DataIC50: 81nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616346(CHEMBL5419493)
Affinity DataIC50: 82nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM4350((2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid ...)
Affinity DataIC50: 87nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616336(CHEMBL5401494)
Affinity DataIC50: 105nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616339(CHEMBL5405329)
Affinity DataIC50: 105nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616348(CHEMBL5409450)
Affinity DataIC50: 109nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616335(CHEMBL5394985)
Affinity DataIC50: 109nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616343(CHEMBL5433941)
Affinity DataIC50: 109nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616337(CHEMBL5440350)
Affinity DataIC50: 112nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616338(CHEMBL5421503)
Affinity DataIC50: 135nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616334(CHEMBL5397576)
Affinity DataIC50: 193nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616342(CHEMBL5427293)
Affinity DataIC50: 196nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616345(CHEMBL5431419)
Affinity DataIC50: 198nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616347(CHEMBL5439235)
Affinity DataIC50: 214nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMultidrug resistance-associated protein 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50512899(CHEMBL4468057)
Affinity DataIC50: 215nMAssay Description:Inhibition of ABCC1 in human NCI-H69AR cells incubated for 180 mins by daunorubicin based fluorescence flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616344(CHEMBL5402273)
Affinity DataIC50: 287nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616333(CHEMBL5402599)
Affinity DataIC50: 314nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616341(CHEMBL5427387)
Affinity DataIC50: 793nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 851nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells incubated for 180 mins by daunorubicin based fluorescence flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 960nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells incubated for 30 mins by calcein AM dye based fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616340(CHEMBL5435709)
Affinity DataIC50: 983nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells incubated for 30 mins by calcein AM dye based fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616347(CHEMBL5439235)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells incubated for 180 mins by daunorubicin based fluorescence flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616347(CHEMBL5439235)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells incubated for 30 mins by calcein AM dye based fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616340(CHEMBL5435709)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells incubated for 180 mins by daunorubicin based fluorescence flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616346(CHEMBL5419493)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells incubated for 30 mins by calcein AM dye based fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616346(CHEMBL5419493)
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells incubated for 180 mins by daunorubicin based fluorescence flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616339(CHEMBL5405329)
Affinity DataIC50: 5.32E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells incubated for 30 mins by calcein AM dye based fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMultidrug resistance-associated protein 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616338(CHEMBL5421503)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of ABCC1 in human NCI-H69AR cells incubated for 180 mins by daunorubicin based fluorescence flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMultidrug resistance-associated protein 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616339(CHEMBL5405329)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of ABCC1 in human NCI-H69AR cells incubated for 180 mins by daunorubicin based fluorescence flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616338(CHEMBL5421503)
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells incubated for 30 mins by calcein AM dye based fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed