Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50020609
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 365 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 380 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 420 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 550 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631868BDBM50631868(CHEMBL5400284)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with LED array by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631873BDBM50631873(CHEMBL5405937)
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 550 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631873BDBM50631873(CHEMBL5405937)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631869BDBM50631869(CHEMBL5401058)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with LED array by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631870BDBM50631870(CHEMBL5428905)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with LED array by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631871BDBM50631871(CHEMBL5418632)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with LED array by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631867BDBM50631867(CHEMBL5422313)
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631864BDBM50631864(CHEMBL5394496)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 380 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631868BDBM50631868(CHEMBL5400284)
Affinity DataIC50: 960nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631869BDBM50631869(CHEMBL5401058)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631875BDBM50631875(CHEMBL5427776)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 420 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631861BDBM50631861(CHEMBL5397433)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 550 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631866BDBM50631866(CHEMBL5427242)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 550 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631867BDBM50631867(CHEMBL5422313)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with LED array by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631872BDBM50631872(CHEMBL5418488)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with LED array by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631865BDBM50631865(CHEMBL5418684)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 550 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631862BDBM50631862(CHEMBL5437164)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 420 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631874BDBM50631874(CHEMBL5398384)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 550 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631866BDBM50631866(CHEMBL5427242)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631863BDBM50631863(CHEMBL5411410)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in presence of illumination with 380 nm light by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631872BDBM50631872(CHEMBL5418488)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631870BDBM50631870(CHEMBL5428905)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631871BDBM50631871(CHEMBL5418632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631861BDBM50631861(CHEMBL5397433)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631864BDBM50631864(CHEMBL5394496)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631865BDBM50631865(CHEMBL5418684)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631862BDBM50631862(CHEMBL5437164)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631863BDBM50631863(CHEMBL5411410)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 1 hrs in dark by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed