Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50019223
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017293BDBM50017293(CHEMBL3287735 | US10647700, Compound GSK126 | US12...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLlSA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616849BDBM50616849(CHEMBL5433886)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLlSA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616852BDBM50616852(CHEMBL5408309)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLlSA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616851BDBM50616851(CHEMBL5404097)
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLlSA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616850BDBM50616850(CHEMBL5402038)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLlSA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616853BDBM50616853(CHEMBL5413031)
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLlSA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616854BDBM50616854(CHEMBL5408277)
Affinity DataIC50: 11nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLlSA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590381BDBM50590381(CHEMBL5173402)
Affinity DataIC50: 64nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLlSA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616855BDBM50616855(CHEMBL5411370)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLlSA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616852BDBM50616852(CHEMBL5408309)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of EZH2 methyltransferase activity in human A2780 cells assessed as reduction in H3K27me3 level incubated for 3 days by Western blot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616853BDBM50616853(CHEMBL5413031)
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of EZH2 methyltransferase activity in human A2780 cells assessed as reduction in H3K27me3 level incubated for 3 days by Western blot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed