Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50019227
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103642BDBM50103642(CHEMBL308954 | TMC-125 | TMC 125 | 4-(6-amino-5-br...)
Affinity DataIC50: 17nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 151585BDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 39nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616933BDBM50616933(CHEMBL5427806)
Affinity DataIC50: 85nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616910BDBM50616910(CHEMBL5425657)
Affinity DataIC50: 88nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616912BDBM50616912(CHEMBL5419852)
Affinity DataIC50: 91nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616921BDBM50616921(CHEMBL5413532)
Affinity DataIC50: 97nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616914BDBM50616914(CHEMBL5419074)
Affinity DataIC50: 97nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616932BDBM50616932(CHEMBL5395688)
Affinity DataIC50: 104nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616922BDBM50616922(CHEMBL5437547)
Affinity DataIC50: 108nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616935BDBM50616935(CHEMBL5423259)
Affinity DataIC50: 108nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616928BDBM50616928(CHEMBL5406818)
Affinity DataIC50: 110nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616909BDBM50616909(CHEMBL5440777)
Affinity DataIC50: 115nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616930BDBM50616930(CHEMBL5423899)
Affinity DataIC50: 117nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616931BDBM50616931(CHEMBL5418212)
Affinity DataIC50: 121nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616927BDBM50616927(CHEMBL5410815)
Affinity DataIC50: 122nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616916BDBM50616916(CHEMBL5420480)
Affinity DataIC50: 122nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616924BDBM50616924(CHEMBL5414170)
Affinity DataIC50: 130nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616897BDBM50616897(CHEMBL5409981)
Affinity DataIC50: 130nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616904BDBM50616904(CHEMBL5412214)
Affinity DataIC50: 130nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616918BDBM50616918(CHEMBL5407066)
Affinity DataIC50: 134nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616920BDBM50616920(CHEMBL5421253)
Affinity DataIC50: 136nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616903BDBM50616903(CHEMBL5405899)
Affinity DataIC50: 137nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121975BDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 138nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616919BDBM50616919(CHEMBL5416739)
Affinity DataIC50: 138nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616905BDBM50616905(CHEMBL5428608)
Affinity DataIC50: 145nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616898BDBM50616898(CHEMBL5414892)
Affinity DataIC50: 154nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616934BDBM50616934(CHEMBL5422435)
Affinity DataIC50: 157nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616923BDBM50616923(CHEMBL5414233)
Affinity DataIC50: 159nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616915BDBM50616915(CHEMBL5402386)
Affinity DataIC50: 159nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616899BDBM50616899(CHEMBL5424986)
Affinity DataIC50: 161nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616929BDBM50616929(CHEMBL5420519)
Affinity DataIC50: 161nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616901BDBM50616901(CHEMBL5394413)
Affinity DataIC50: 163nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616911BDBM50616911(CHEMBL5414371)
Affinity DataIC50: 164nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616913BDBM50616913(CHEMBL5433313)
Affinity DataIC50: 171nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616925BDBM50616925(CHEMBL5430724)
Affinity DataIC50: 175nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616907BDBM50616907(CHEMBL5436275)
Affinity DataIC50: 178nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616917BDBM50616917(CHEMBL5414187)
Affinity DataIC50: 178nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616900BDBM50616900(CHEMBL5422872)
Affinity DataIC50: 194nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616926BDBM50616926(CHEMBL5436123)
Affinity DataIC50: 199nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616906BDBM50616906(CHEMBL5406045)
Affinity DataIC50: 205nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50207551BDBM50207551(CHEMBL3977345)
Affinity DataIC50: 208nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616902BDBM50616902(CHEMBL5428814)
Affinity DataIC50: 228nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014323BDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 235nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616908BDBM50616908(CHEMBL5411923)
Affinity DataIC50: 328nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase assessed as inhibition of biotin-dUTP incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090677BDBM50090677(CHEMBL1109 | 4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-...)
Affinity DataIC50: 627nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616932BDBM50616932(CHEMBL5395688)
Affinity DataIC50: 6.54E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616932BDBM50616932(CHEMBL5395688)
Affinity DataIC50: 9.58E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616931BDBM50616931(CHEMBL5418212)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616931BDBM50616931(CHEMBL5418212)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616932BDBM50616932(CHEMBL5395688)
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
Displayed 1 to 50 (of 55 total ) | Next | Last >>
Jump to: