Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50018416
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303503BDBM50303503(CHEMBL4160782 | US10858316, Compound SF-5-141)
Affinity DataKi:  120nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to MCL-1 (172 to 327 residues) (unknown origin) assessed as inhibition constant by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473880BDBM473880(5-(4-(4-chloro-3,5- dimethylphenoxy)- N-isobutylph...)
Affinity DataKi:  586nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473868BDBM473868(4-(N-benzyl-4-(4- chloro-3,5- dimethylphenoxy) phe...)
Affinity DataKi:  629nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473862BDBM473862(3-(4-(4-chloro-3,5- dimethylphenoxy)- N- isobutylp...)
Affinity DataKi:  778nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473876BDBM473876(3-(4-(4-chloro-3,5- dimethylphenoxy)- N-isobutylph...)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473862BDBM473862(3-(4-(4-chloro-3,5- dimethylphenoxy)- N- isobutylp...)
Affinity DataKi:  1.63E+3nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473868BDBM473868(4-(N-benzyl-4-(4- chloro-3,5- dimethylphenoxy) phe...)
Affinity DataKi:  1.67E+3nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473867BDBM473867(4-(N-benzyl-[1,1'- biphenyl]-4- ylsulfonamido)-2- ...)
Affinity DataKi:  1.71E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608153BDBM50608153(CHEMBL5269202)
Affinity DataKi:  1.76E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608153BDBM50608153(CHEMBL5269202)
Affinity DataKi:  1.91E+3nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473849BDBM473849(4-(4-(4-chloro-3,5- dimethylphenoxy)- N-isobutylph...)
Affinity DataKi:  2.06E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473859BDBM473859(2-hydroxy-4-(N- isobutyl-4-(p- tolyloxy)phenyl- su...)
Affinity DataKi:  2.26E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473844BDBM473844(1-((4-(4-chloro-3,5- dimethylphenoxy) phenyl) sulf...)
Affinity DataKi:  2.73E+3nMAssay Description:Binding affinity to MCL-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473861BDBM473861(4-(4-(2,4- dichlorophenoxy)- N-isobutylphenyl- sul...)
Affinity DataKi:  2.74E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473880BDBM473880(5-(4-(4-chloro-3,5- dimethylphenoxy)- N-isobutylph...)
Affinity DataKi:  2.91E+3nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473860BDBM473860(4-(4-(3,5- dimethylphenoxy)- N-isobutylphenyl- sul...)
Affinity DataKi:  2.96E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473844BDBM473844(1-((4-(4-chloro-3,5- dimethylphenoxy) phenyl) sulf...)
Affinity DataKi:  3.56E+3nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473852BDBM473852(2-hydroxy-4-(N- isobutyl-[1,1'- biphenyl]-4- ylsul...)
Affinity DataKi:  4.11E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303503BDBM50303503(CHEMBL4160782 | US10858316, Compound SF-5-141)
Affinity DataKi:  5.01E+3nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473864BDBM473864(4-(N-cyclopentyl- [1,1'- biphenyl]-4- ylsulfonamid...)
Affinity DataKi:  5.24E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473858BDBM473858(2-hydroxy-4-(N- isobutyl-4- phenoxyphenyl- sulfona...)
Affinity DataKi:  5.77E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473878BDBM473878(US10858316, Compound jy-5-299)
Affinity DataKi:  7.51E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473879BDBM473879(2-hydroxy-5-(N- isobutyl-[1,1'- biphenyl]-4- ylsul...)
Affinity DataKi:  8.70E+3nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473852BDBM473852(2-hydroxy-4-(N- isobutyl-[1,1'- biphenyl]-4- ylsul...)
Affinity DataKi:  1.08E+4nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473866BDBM473866(4-(N- benzyl- naphthalene-2- sulfonamido)-2- hydro...)
Affinity DataKi:  1.14E+4nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473869BDBM473869(2-hydroxy-4-(4- phenoxyphenyl- sulfonamido) benzoi...)
Affinity DataKi:  1.37E+4nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473851BDBM473851(2-hydroxy-4-(N- isobutylnaphthalene- 2-sulfonamido...)
Affinity DataKi:  1.38E+4nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473879BDBM473879(2-hydroxy-5-(N- isobutyl-[1,1'- biphenyl]-4- ylsul...)
Affinity DataKi:  1.39E+4nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473847BDBM473847(4-(N-isobutyl-[1,1'- biphenyl]-4- ylsulfonamido) b...)
Affinity DataKi:  1.67E+4nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473854BDBM473854(4-(4-bromo-N- isobutylphenyl- sulfonamido)-2- hydr...)
Affinity DataKi:  1.69E+4nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473858BDBM473858(2-hydroxy-4-(N- isobutyl-4- phenoxyphenyl- sulfona...)
Affinity DataKi:  1.79E+4nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473863BDBM473863(4-(N- cyclopentyl- naphthalene- 2-sulfonamido)-2- ...)
Affinity DataKi:  2.47E+4nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473851BDBM473851(2-hydroxy-4-(N- isobutylnaphthalene- 2-sulfonamido...)
Affinity DataKi:  4.31E+4nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473878BDBM473878(US10858316, Compound jy-5-299)
Affinity DataKi:  4.46E+4nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473877BDBM473877(2-hydroxy-5-(N- isobutylphenyl- sulfonamido) benzo...)
Affinity DataKi:  4.65E+4nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473877BDBM473877(2-hydroxy-5-(N- isobutylphenyl- sulfonamido) benzo...)
Affinity DataKi:  4.93E+4nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473857BDBM473857(2-hydroxy-4-(N- isobutyl-4- methylphenyl- sulfonam...)
Affinity DataKi:  6.12E+4nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473872BDBM473872(3-(N- isobutyl- naphthalene-2- sulfonamido) benzoi...)
Affinity DataKi:  6.17E+4nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473853BDBM473853(4-(4-fluoro-N- isobutylphenyl- sulfonamido)- 2-hyd...)
Affinity DataKi:  9.94E+4nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473850BDBM473850(2-hydroxy-4-(N- isobutylphenyl- sulfonamido) benzo...)
Affinity DataKi:  1.54E+5nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473875BDBM473875(3-(N-isobutyl-4- methylphenyl- sulfonamido) benzoi...)
Affinity DataKi:  1.55E+5nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473850BDBM473850(2-hydroxy-4-(N- isobutylphenyl- sulfonamido) benzo...)
Affinity DataKi:  1.92E+5nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473848BDBM473848(4-(4-fluoro-N- isobutylphenyl- sulfonamido) benzoi...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473871BDBM473871(3-(N- isobutylphenyl- sulfonamido) benzoic acid | ...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473874BDBM473874(3-(4-fluoro-N- isobutylphenyl- sulfonamido) benzoi...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473873BDBM473873(3-(N-isobutyl-[1,1'- biphenyl]-4- ylsulfonamido) b...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473845BDBM473845(4-(N- isobutylphenyl- sulfonamido) benzoic acid | ...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 473846BDBM473846(4-(N- isobutylnaphthalene- 2-sulfonamido) benzoic ...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to 6His-MBP tagged recombinant human MCL-1 (172 to 327 residues) expressed in Escherichia coli assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed