Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50020759
TargetC-X-C chemokine receptor type 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50169045((R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propana...)
Affinity DataIC50: 1nMAssay Description:Displacement of 125I-IL-8 from CXCR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetC-X-C chemokine receptor type 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50633395(Danirixin | Danirixine | Danirixina | Gsk1325756 |...)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-CXCL8 from human CXCR2 transfected in CHO-K1 cell membrane incubated for 45 mins by scintillation proximity binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetC-X-C chemokine receptor type 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50203012(SB-225002 | 1-(2-bromophenyl)-3-(2-hydroxy-4-nitro...)
Affinity DataIC50: 22nMAssay Description:Displacement of 125I-IL-8 from CXCR2 (unknown origin) expressed in CHO cell membrane incubated for 1 hr by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetC-X-C chemokine receptor type 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50169045((R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propana...)
Affinity DataIC50: 100nMAssay Description:Displacement of 125I-IL-8 from CXCR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed