Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50018825
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612913(CHEMBL5267199)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612904(CHEMBL5274251)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612913(CHEMBL5267199)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612908(CHEMBL5281631)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612900(CHEMBL5286305)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612906(CHEMBL5279191)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612907(CHEMBL5281151)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612909(CHEMBL5284123)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612912(CHEMBL5266872)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612912(CHEMBL5266872)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612904(CHEMBL5274251)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612900(CHEMBL5286305)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612905(CHEMBL5271234)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612908(CHEMBL5281631)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612907(CHEMBL5281151)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612903(CHEMBL5268293)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612910(CHEMBL5284849)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612911(CHEMBL5269031)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612906(CHEMBL5279191)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612909(CHEMBL5284123)
Affinity DataEC50:  340nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612905(CHEMBL5271234)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612911(CHEMBL5269031)
Affinity DataEC50:  440nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612897(CHEMBL5283585)
Affinity DataEC50:  650nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612903(CHEMBL5268293)
Affinity DataEC50:  740nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612910(CHEMBL5284849)
Affinity DataEC50:  810nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50012905(CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...)
Affinity DataEC50:  990nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612902(CHEMBL5277807)
Affinity DataEC50: >1.20E+3nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612901(CHEMBL5269734)
Affinity DataEC50: >1.20E+3nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612897(CHEMBL5283585)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50012905(CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...)
Affinity DataEC50:  2.85E+3nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612901(CHEMBL5269734)
Affinity DataEC50: >3.70E+3nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612902(CHEMBL5277807)
Affinity DataEC50: >3.70E+3nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612896(CHEMBL5290804)
Affinity DataEC50: >1.10E+4nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612898(CHEMBL5290997)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612896(CHEMBL5290804)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612899(CHEMBL5281233)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612898(CHEMBL5290997)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612899(CHEMBL5281233)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed