Compile Data Set for Download or QSAR
Report error Found 79 Enz. Inhib. hit(s) with all data for entry = 50019243
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617074(CHEMBL5417158)
Affinity DataEC50:  280nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617085(CHEMBL5424638)
Affinity DataEC50:  380nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617085(CHEMBL5424638)
Affinity DataIC50: 610nMAssay Description:Agonist activity at human 6His-tagged recombinant STING G230A/R293Q double mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617084(CHEMBL5414312)
Affinity DataIC50: 770nMAssay Description:Agonist activity at human 6His-tagged recombinant STING G230A/R293Q double mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617083(CHEMBL5416014)
Affinity DataIC50: 810nMAssay Description:Agonist activity at human 6His-tagged recombinant STING G230A/R293Q double mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617083(CHEMBL5416014)
Affinity DataIC50: 930nMAssay Description:Agonist activity at mouse 6His-tagged recombinant STING CTD (144 to 378 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617085(CHEMBL5424638)
Affinity DataIC50: 960nMAssay Description:Agonist activity at mouse 6His-tagged recombinant STING CTD (144 to 378 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617085(CHEMBL5424638)
Affinity DataIC50: 1.06E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R232H mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617083(CHEMBL5416014)
Affinity DataIC50: 1.11E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R232H mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617085(CHEMBL5424638)
Affinity DataIC50: 1.12E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R293Q mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617085(CHEMBL5424638)
Affinity DataIC50: 1.15E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant wild type STING CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617082(CHEMBL5432208)
Affinity DataIC50: 1.17E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING G230A/R293Q double mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617084(CHEMBL5414312)
Affinity DataIC50: 1.21E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R232H mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50566278(CHEMBL4867353)
Affinity DataIC50: 1.39E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING G230A/R293Q double mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50566278(CHEMBL4867353)
Affinity DataIC50: 1.60E+3nMAssay Description:Agonist activity at mouse 6His-tagged recombinant STING CTD (144 to 378 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617084(CHEMBL5414312)
Affinity DataIC50: 1.62E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R293Q mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617084(CHEMBL5414312)
Affinity DataIC50: 1.75E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant wild type STING CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617083(CHEMBL5416014)
Affinity DataIC50: 1.89E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant wild type STING CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617084(CHEMBL5414312)
Affinity DataIC50: 1.90E+3nMAssay Description:Agonist activity at mouse 6His-tagged recombinant STING CTD (144 to 378 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617083(CHEMBL5416014)
Affinity DataIC50: 2.27E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R293Q mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617082(CHEMBL5432208)
Affinity DataEC50:  2.27E+3nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617084(CHEMBL5414312)
Affinity DataEC50:  2.78E+3nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50566278(CHEMBL4867353)
Affinity DataEC50:  3.03E+3nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM453551(4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...)
Affinity DataEC50:  3.51E+3nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617083(CHEMBL5416014)
Affinity DataEC50:  3.52E+3nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617074(CHEMBL5417158)
Affinity DataIC50: 3.57E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R232H mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617074(CHEMBL5417158)
Affinity DataIC50: 4.35E+3nMAssay Description:Agonist activity at mouse 6His-tagged recombinant STING CTD (144 to 378 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617081(CHEMBL5396779)
Affinity DataEC50:  4.50E+3nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617082(CHEMBL5432208)
Affinity DataIC50: 4.79E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R232H mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617082(CHEMBL5432208)
Affinity DataIC50: 5.06E+3nMAssay Description:Agonist activity at mouse 6His-tagged recombinant STING CTD (144 to 378 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617074(CHEMBL5417158)
Affinity DataEC50:  5.22E+3nMAssay Description:Agonist activity at mouse STING in mouse RAW-Lucia ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617074(CHEMBL5417158)
Affinity DataIC50: 5.60E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant wild type STING CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617077(CHEMBL5437805)
Affinity DataEC50:  5.96E+3nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617082(CHEMBL5432208)
Affinity DataIC50: 5.97E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant wild type STING CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50566278(CHEMBL4867353)
Affinity DataIC50: 6.16E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R232H mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617082(CHEMBL5432208)
Affinity DataIC50: 6.46E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R293Q mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50566278(CHEMBL4867353)
Affinity DataIC50: 8.02E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R293Q mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617074(CHEMBL5417158)
Affinity DataIC50: 8.40E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING R293Q mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617074(CHEMBL5417158)
Affinity DataIC50: 8.97E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant STING G230A/R293Q double mutant CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50566278(CHEMBL4867353)
Affinity DataIC50: 9.81E+3nMAssay Description:Agonist activity at human 6His-tagged recombinant wild type STING CTD (139 to 37 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617063(CHEMBL5408678)
Affinity DataEC50:  1.05E+4nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617061(CHEMBL5417810)
Affinity DataEC50:  1.15E+4nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617085(CHEMBL5424638)
Affinity DataEC50:  1.29E+4nMAssay Description:Agonist activity at mouse STING in mouse RAW-Lucia ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617065(CHEMBL5428811)
Affinity DataEC50:  1.76E+4nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617071(CHEMBL5419901)
Affinity DataEC50:  1.79E+4nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617066(CHEMBL5416022)
Affinity DataEC50:  2.06E+4nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617078(CHEMBL5411646)
Affinity DataEC50:  2.13E+4nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617068(CHEMBL5397751)
Affinity DataEC50:  2.23E+4nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617067(CHEMBL5397964)
Affinity DataEC50:  2.28E+4nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50617062(CHEMBL5394539)
Affinity DataEC50:  2.99E+4nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells incubated for 24 hrs in presence of PMA by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
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