Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50018998
TargetRetinoic acid receptor RXR-alpha(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50391814(CHEMBL2146901)
Affinity DataKd:  280nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant using PGC-1al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50391814(CHEMBL2146901)
Affinity DataKd:  330nMAssay Description:Binding affinity to human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer assessed as dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50339081(6-[Ethyl-(3-isobutoxy-4-isopropylphenyl)amino]nico...)
Affinity DataKd:  340nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant using PGC-1al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataIC50: 389nMAssay Description:Displacement of CU-6PMN from human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50339081(6-[Ethyl-(3-isobutoxy-4-isopropylphenyl)amino]nico...)
Affinity DataIC50: 394nMAssay Description:Displacement of CU-6PMN from human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50391814(CHEMBL2146901)
Affinity DataIC50: 431nMAssay Description:Displacement of CU-6PMN from human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataKd:  650nMAssay Description:Binding affinity to human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer assessed as dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50530499(CHEMBL4449685)
Affinity DataKd:  1.11E+3nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant using PGC-1al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50339081(6-[Ethyl-(3-isobutoxy-4-isopropylphenyl)amino]nico...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant using SRC1 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50391814(CHEMBL2146901)
Affinity DataKd:  1.59E+3nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant using SRC1 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50210259(all-cis-docosa-4,7,10,13,16,19-hexaenoic acid | Do...)
Affinity DataIC50: 4.82E+3nMAssay Description:Displacement of CU-6PMN from human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50530499(CHEMBL4449685)
Affinity DataKd:  1.32E+4nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant using SRC1 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed