Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50019690
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 30nMAssay Description:Inhibition of HIV1 Reverse transcriptase incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)
Affinity DataIC50: 160nMAssay Description:Inhibition of HIV1 Reverse transcriptase incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50621833(CHEMBL5410709)
Affinity DataIC50: 280nMAssay Description:Inhibition of HIV1 Reverse transcriptase incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50621835(CHEMBL5395699)
Affinity DataIC50: 350nMAssay Description:Inhibition of HIV1 Reverse transcriptase incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50621832(CHEMBL5397495)
Affinity DataIC50: 350nMAssay Description:Inhibition of HIV1 Reverse transcriptase incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 Reverse transcriptase incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50621834(CHEMBL5412528)
Affinity DataIC50: 700nMAssay Description:Inhibition of HIV1 Reverse transcriptase incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50621832(CHEMBL5397495)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac and sulfaphenazole as substrate preincubated for 5 mins followed by NADPH addition an...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50621832(CHEMBL5397495)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed