Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50019699
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 391nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 617nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 652nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 717nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 956nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 966nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 1.21E+3nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 1.85E+3nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 2.01E+3nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 4.78E+3nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 5.19E+3nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: 8.60E+3nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich
Curated by ChEMBL
Eth Zurich
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair
Ligand InfoSimilars


3D Structure (crystal)













