Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50020417
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629794BDBM50629794(CHEMBL5396377)
Affinity DataIC50: 0.141nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629794BDBM50629794(CHEMBL5396377)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629789BDBM50629789(CHEMBL5401656)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629789BDBM50629789(CHEMBL5401656)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629793BDBM50629793(CHEMBL5413359)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629791BDBM50629791(CHEMBL5427101)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629792BDBM50629792(CHEMBL5400638)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629788BDBM50629788(CHEMBL5393994)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629790BDBM50629790(CHEMBL5423458)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629786BDBM50629786(CHEMBL5412104)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629785BDBM50629785(CHEMBL5408911)
Affinity DataIC50: 17nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 533526BDBM533526(jm2c00120, Compound 25)
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629787BDBM50629787(CHEMBL5431675)
Affinity DataIC50: 26nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629784BDBM50629784(CHEMBL5411560)
Affinity DataIC50: 52nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629784BDBM50629784(CHEMBL5411560)
Affinity DataIC50: 62nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629782BDBM50629782(CHEMBL5423096)
Affinity DataIC50: 130nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629781BDBM50629781(CHEMBL5427053)
Affinity DataIC50: 187nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629783BDBM50629783(CHEMBL5428251)
Affinity DataIC50: 274nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378739BDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 360nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629780BDBM50629780(CHEMBL5407468)
Affinity DataIC50: 383nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629779BDBM50629779(CHEMBL5438762)
Affinity DataIC50: 468nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629778BDBM50629778(CHEMBL5394180)
Affinity DataIC50: 573nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629777BDBM50629777(CHEMBL5424971)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629776BDBM50629776(CHEMBL5415934)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629775BDBM50629775(CHEMBL5427720)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629779BDBM50629779(CHEMBL5438762)
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629774BDBM50629774(CHEMBL5400055)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629784BDBM50629784(CHEMBL5411560)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of N-terminal 6His-tagged human RNMT activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and [3H]-SAM as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629779BDBM50629779(CHEMBL5438762)
Affinity DataIC50: 5.62E+4nMAssay Description:Inhibition of N-terminal 6His-tagged human RNMT activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and [3H]-SAM as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629789BDBM50629789(CHEMBL5401656)
Affinity DataIC50: 5.65E+4nMAssay Description:Inhibition of N-terminal 6His-tagged human RNMT activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and [3H]-SAM as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629794BDBM50629794(CHEMBL5396377)
Affinity DataIC50: 1.65E+5nMAssay Description:Inhibition of N-terminal 6His-tagged human RNMT activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and [3H]-SAM as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed