Compile Data Set for Download or QSAR
Report error Found 90 Enz. Inhib. hit(s) with all data for entry = 50022266
TargetSigma intracellular receptor 2(Rat)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50604966(CHEMBL5175530)
Affinity DataKi:  5.10nMAssay Description:Binding affinity to sigma 2 receptor in rat PC12 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650029(CHEMBL5624846)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650046(CHEMBL5625042)
Affinity DataKi:  8nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50621493(CHEMBL5401938)
Affinity DataKi:  9.20nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650022(CHEMBL5631181)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650022(CHEMBL5631181)
Affinity DataKi:  9.20nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50604966(CHEMBL5175530)
Affinity DataKi:  11nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650016(CHEMBL5630078)
Affinity DataKi:  12nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650047(CHEMBL5630062)
Affinity DataKi:  12nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650036(CHEMBL5624896)
Affinity DataKi:  12nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50621493(CHEMBL5401938)
Affinity DataKi:  16nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650026(CHEMBL5630941)
Affinity DataKi:  16nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650028(CHEMBL5630613)
Affinity DataKi:  17nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650039(CHEMBL5631105)
Affinity DataKi:  18nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650027(CHEMBL5624996)
Affinity DataKi:  21nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650031(CHEMBL5625109)
Affinity DataKi:  21nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650028(CHEMBL5630613)
Affinity DataKi:  21nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650036(CHEMBL5624896)
Affinity DataKi:  22nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650045(CHEMBL5630374)
Affinity DataKi:  22nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50604968(CHEMBL5190189)
Affinity DataKi:  23nMAssay Description:Binding affinity to sigma 2 receptor in rat PC12 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650024(CHEMBL5624962)
Affinity DataKi:  24nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650023(CHEMBL5625019)
Affinity DataKi:  24nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50621494(CHEMBL5440859)
Affinity DataKi:  26nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650027(CHEMBL5624996)
Affinity DataKi:  26nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650030(CHEMBL5630963)
Affinity DataKi:  27nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650037(CHEMBL5631035)
Affinity DataKi:  28nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50604966(CHEMBL5175530)
Affinity DataKi:  31nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650044(CHEMBL5630747)
Affinity DataKi:  32nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650016(CHEMBL5630078)
Affinity DataKi:  33nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650017(CHEMBL5624574)
Affinity DataKi:  34nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650051(CHEMBL5630149)
Affinity DataKi:  35nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650041(CHEMBL5624542)
Affinity DataKi:  37nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650041(CHEMBL5624542)
Affinity DataKi:  37nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650022(CHEMBL5631181)
Affinity DataKi:  38nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50604969(CHEMBL5189158)
Affinity DataKi:  46nMAssay Description:Binding affinity to sigma 2 receptor in rat PC12 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650020(CHEMBL5630466)
Affinity DataKi:  47nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650037(CHEMBL5631035)
Affinity DataKi:  50nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650017(CHEMBL5624574)
Affinity DataKi:  51nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650032(CHEMBL5624713)
Affinity DataKi:  52nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650049(CHEMBL5630724)
Affinity DataKi:  52nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650051(CHEMBL5630149)
Affinity DataKi:  53nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650033(CHEMBL5630104)
Affinity DataKi:  53nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650025(CHEMBL5624651)
Affinity DataKi:  57nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650040(CHEMBL5630130)
Affinity DataKi:  58nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650034(CHEMBL5631099)
Affinity DataKi:  58nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650045(CHEMBL5630374)
Affinity DataKi:  58nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650043(CHEMBL5631121)
Affinity DataKi:  58nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor transfected in human HEK293T cells assessed as inhibition constant in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650046(CHEMBL5625042)
Affinity DataKi:  59nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650048(CHEMBL5630787)
Affinity DataKi:  61nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50650031(CHEMBL5625109)
Affinity DataKi:  68nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in HEK293 cells assessed as inhibition constant by radioligand competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
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