Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50022272
LigandChemical structure of BindingDB Monomer ID 50650150BDBM50650150(CHEMBL4516422)
Affinity DataEC50:  0.650nMAssay Description:Agonist activity at TRPA1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 452524BDBM452524(US10710994, Example 2 | US10710994, Example 36 | 1...)
Affinity DataIC50: 7nMAssay Description:Agonist activity at rat TRPA1 transfected in HEK293F cells assessed as increase in Ca2+ influx by FLIPR calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 25525BDBM25525(CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...)
Affinity DataEC50:  90nMAssay Description:Antagonist activity at TRPA1 (unknown origin) expressed in HEK293T cells assessed as inhibition of agonist induced channel current by whole-cell patc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318498BDBM50318498(2-(7-fluoro-1-isobutyl-2-oxoindolin-3-ylidene)acet...)
Affinity DataIC50: 510nMAssay Description:Agonist activity at rat recombinant TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium accumulation by Fluo4-AM based assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50638594BDBM50638594(CHEMBL5558033)
Affinity DataEC50:  2.39E+3nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50638594BDBM50638594(CHEMBL5558033)
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibition of TRPA1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50650157BDBM50650157(CHEMBL5629921)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human recombinant TRPV1 over expressed in HEK293 cells assessed as increase in intracellular calcium level by measuring efficacy ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50364440BDBM50364440(CHEMBL1950593)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of TRPA1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50364445BDBM50364445(CHEMBL1950590)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of TRPA1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50650156BDBM50650156(CHEMBL5630882)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human recombinant TRPV1 over expressed in HEK293 cells assessed as increase in intracellular calcium level by measuring efficacy ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50364438BDBM50364438(CHEMBL1950595)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of TRPA1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50650153BDBM50650153(LEUCETTAMOL A)
Affinity DataEC50:  3.70E+3nMAssay Description:Agonist activity at human recombinant TRPV1 over expressed in HEK293 cells assessed as increase in intracellular calcium level by measuring efficacy ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50364444BDBM50364444(CHEMBL487732)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of TRPA1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50467427BDBM50467427(CHEMBL4289050)
Affinity DataIC50: 5.07E+3nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467427BDBM50467427(CHEMBL4289050)
Affinity DataIC50: 5.43E+3nMAssay Description:Inhibition of human PDE4B by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50650159BDBM50650159(CHEMBL1766307)
Affinity DataEC50:  5.63E+3nMAssay Description:Antagonist activity at human recombinant TRPA1 transfected in HEK293T cells assessed as increase in Ca2+ influx by FLIPR calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50650155BDBM50650155(CHEMBL5630059)
Affinity DataEC50:  5.90E+3nMAssay Description:Agonist activity at human recombinant TRPV1 over expressed in HEK293 cells assessed as increase in intracellular calcium level by measuring efficacy ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50638594BDBM50638594(CHEMBL5558033)
Affinity DataIC50: 8.64E+3nMAssay Description:Inhibition of TRPV1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50650154BDBM50650154(CHEMBL510466)
Affinity DataEC50:  9.40E+3nMAssay Description:Agonist activity at human recombinant TRPV1 over expressed in HEK293 cells assessed as increase in intracellular calcium level by measuring efficacy ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50650158BDBM50650158(CHEMBL5624906)
Affinity DataEC50:  9.70E+3nMAssay Description:Agonist activity at human recombinant TRPV1 over expressed in HEK293 cells assessed as increase in intracellular calcium level by measuring efficacy ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50479044BDBM50479044(CHEBI:80845 | Liquiritin)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of TRPV1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50364438BDBM50364438(CHEMBL1950595)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TRPV1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50364440BDBM50364440(CHEMBL1950593)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TRPV1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50479044BDBM50479044(CHEBI:80845 | Liquiritin)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of TRPA1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50441016BDBM50441016((Z)-Ligustilide | CHEMBL481246)
Affinity DataEC50:  4.40E+4nMAssay Description:Antagonist activity at mouse TRPA1 expressed in HEK293F cells as increase in Ca2+ influx by FLIPR calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50364444BDBM50364444(CHEMBL487732)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of TRPV1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50364445BDBM50364445(CHEMBL1950590)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of TRPV1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50650151BDBM50650151(CHEMBL5630743)
Affinity DataEC50:  4.22E+5nMAssay Description:Agonist activity at full length mouse TRPA1 transfected in HEK293F cells assessed as increase in Ca2+ influx by FLIPR calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50650152BDBM50650152(CHEMBL4519263)
Affinity DataEC50:  5.10E+5nMAssay Description:Agonist activity at full length mouse TRPA1 transfected in HEK293F cells assessed as increase in Ca2+ influx by FLIPR calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50241315BDBM50241315(Z-butylidenephthalide | (Z)-3-butylideneisobenzofu...)
Affinity DataEC50:  5.39E+5nMAssay Description:Agonist activity at full length mouse TRPA1 transfected in HEK293F cells assessed as increase in Ca2+ influx by FLIPR calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed