Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50019255
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataIC50: 4.30nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM119448(US8686018, 107)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM119448(US8686018, 107)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at EP4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50193922(N-(5-bromo-2-methoxyphenylsulfonyl)-3-(2-(naphthal...)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at EP3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617199(CHEMBL5435929)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617196(CHEMBL5427309)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617198(CHEMBL5427471)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617197(CHEMBL5430749)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]-PGE2 from human EP4 receptor membrane measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617201(CHEMBL5426990)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617196(CHEMBL5427309)
Affinity DataKi:  144nMAssay Description:Displacement of [3H]-PGE2 from human EP4 receptor membrane measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617202(CHEMBL5433739)
Affinity DataIC50: 569nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM119448(US8686018, 107)
Affinity DataIC50: 928nMAssay Description:Antagonist activity at EP2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617203(CHEMBL5419747)
Affinity DataIC50: 2.28E+3nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617196(CHEMBL5427309)
Affinity DataKi: >6.40E+3nMAssay Description:Displacement of [3H]-PGE2 from EP3 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataKi: >6.40E+3nMAssay Description:Displacement of [3H]-PGE2 from EP3 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617196(CHEMBL5427309)
Affinity DataKi: >8.80E+3nMAssay Description:Displacement of [3H]-PGE2 from EP2 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataKi: >8.80E+3nMAssay Description:Displacement of [3H]-PGE2 from EP2 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617196(CHEMBL5427309)
Affinity DataKi: >9.60E+3nMAssay Description:Displacement of [3H]-PGE2 from EP1 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataKi: >9.60E+3nMAssay Description:Displacement of [3H]-PGE2 from EP1 receptor membrane (unknown origin) measured after 2 hrs by Microscint-O scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM119448(US8686018, 107)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at EP1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at EP2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at EP1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM119448(US8686018, 107)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at EP3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at EP3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617204(CHEMBL5428190)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human EP4 receptor overexpressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP formation preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Arromax Pharmatech Co.

Curated by ChEMBL
LigandPNGBDBM50617200(CHEMBL5418164)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed