Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50022288
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 85nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650336(CHEMBL5630569)
Affinity DataIC50: 250nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 570nMAssay Description:Inhibition of full length wild type recombinant human SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650332(CHEMBL5630341)
Affinity DataIC50: 720nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650336(CHEMBL5630569)
Affinity DataIC50: 840nMAssay Description:Inhibition of full length wild type recombinant human SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650326(CHEMBL5624527)
Affinity DataIC50: 970nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650333(CHEMBL5630927)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650332(CHEMBL5630341)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of full length wild type recombinant human SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650329(CHEMBL5630556)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650326(CHEMBL5624527)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of full length wild type recombinant human SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650334(CHEMBL5630514)
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650324(CHEMBL5630632)
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650323(CHEMBL5630446)
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650328(CHEMBL5631084)
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650331(CHEMBL5631135)
Affinity DataIC50: 4.51E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650325(CHEMBL5630354)
Affinity DataIC50: 4.95E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650327(CHEMBL5630189)
Affinity DataIC50: 5.43E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650335(CHEMBL5630491)
Affinity DataIC50: 5.53E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650322(CHEMBL5630888)
Affinity DataIC50: 5.89E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 6.49E+3nMAssay Description:Inhibition of full length recombinant human SHP2 E76K mutant (1 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650336(CHEMBL5630569)
Affinity DataIC50: 6.88E+3nMAssay Description:Inhibition of full length recombinant human SHP2 E76K mutant (1 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650330(CHEMBL5630102)
Affinity DataIC50: 6.99E+3nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650326(CHEMBL5624527)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human SHP2 PTPase activity (219 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650324(CHEMBL5630632)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human SHP2 PTPase activity (219 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650324(CHEMBL5630632)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length recombinant human SHP1 (1 to 570 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human SHP2 PTPase activity (219 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650336(CHEMBL5630569)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human SHP2 PTPase activity (219 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650332(CHEMBL5630341)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human SHP2 PTPase activity (219 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length recombinant human SHP1 (1 to 570 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650336(CHEMBL5630569)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length recombinant human SHP1 (1 to 570 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650332(CHEMBL5630341)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length recombinant human SHP1 (1 to 570 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650326(CHEMBL5624527)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length recombinant human SHP1 (1 to 570 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed