Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50022399
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651814(CHEMBL5639410)
Affinity DataKi:  0.00700nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50479982(CHEBI:63628 | Aptivus | Tipranavir | U-140690 | US...)
Affinity DataKi:  0.00800nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651815(CHEMBL5641569)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651817(CHEMBL5639643)
Affinity DataKi:  0.100nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651816(CHEMBL5646997)
Affinity DataKi:  0.120nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGag polyprotein(Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50649396(Lenacapavir | GS-6207 | GS-714207 | GS-CA-2 | GS-C...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to HIV1 Gag assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651813(CHEMBL5646928)
Affinity DataKi:  1.20nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGag polyprotein(Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651823(CHEMBL5641856)
Affinity DataKd:  2.40nMAssay Description:Binding affinity to HIV1 Gag assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50163751(CHEMBL3799799)
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]MIP-1alpha from CCR5 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651821(CHEMBL5646668)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]MIP-1alpha from CCR5 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651819(CHEMBL5647394)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]MIP-1alpha from CCR5 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50400796(CHEMBL2203614)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]MIP-1alpha from CCR5 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651812(CHEMBL5646760)
Affinity DataKi:  35nMAssay Description:Inhibition of HIV-1 protease expressed in Escherichia coli incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM770(4-hydroxy-6-(1-phenylbutan-2-yl)-3-(1-phenylpropyl...)
Affinity DataKi:  38nMAssay Description:Inhibition of HIV-1 protease expressed in Escherichia coli incubated for 90 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651818(CHEMBL5646686)
Affinity DataIC50: 45nMAssay Description:Displacement of [125I]MIP-1alpha from CCR5 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651822(CHEMBL499273)
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV-1 integraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50480834(CHEMBL573644)
Affinity DataIC50: 220nMAssay Description:Inhibition of HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50457456(CHEMBL2011438 | UK-107543)
Affinity DataIC50: 400nMAssay Description:Displacement of [125I]MIP-1alpha from CCR5 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50651820(CHEMBL5646702)
Affinity DataIC50: 580nMAssay Description:Displacement of [125I]MIP-1alpha from CCR5 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM768(4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one | CH...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50480766(CHEBI:16311 | 2''-Deoxycytidine 5''-Triphosphate |...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to human DNA polymerase gamma assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50138406([(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-o...)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to human DNA polymerase gamma assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50138405([(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-...)
Affinity DataKd:  6.30E+4nMAssay Description:Binding affinity to human DNA polymerase gamma assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)