Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50022400
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651829(CHEMBL5647371)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of IRAK4 (unknown origin) by Ambit kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50549243(CHEMBL4791626 | US11897863, Example 1)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of IRAK4 (unknown origin) by Ambit kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM317277(US9617282, Example 47)
Affinity DataIC50: 1nMAssay Description:Inhibition of IRAK4 (unknown origin) by discoverX kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50040805(CHEMBL3361255)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of IRAK4 (unknown origin) by Kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651828(CHEMBL5639235)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IRAK4 (unknown origin) by Ambit kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclic GMP-AMP synthase(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651824(CHEMBL5641551)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of cyclic GMP-AMP synthase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM395296(N-[2-(3-Hydroxy-3-methylbutyl)-6-(2-hydroxypropan-...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of IRAK4 (unknown origin) by Ambit kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50040806(CHEMBL3361254)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of IRAK4 (unknown origin) by Kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50549242(CHEMBL4797475)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of IRAK4 (unknown origin) by Ambit kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651825(CHEMBL5647673)
Affinity DataIC50: 10nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM395297(N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)...)
Affinity DataIC50: 12nMAssay Description:Inhibition of IRAK4 (unknown origin) by Ambit kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50322535(3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-meth...)
Affinity DataIC50: 67nMAssay Description:Inhibition of wild type human IRAK4 (164 to 460 residues)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651826(CHEMBL5647357)
Affinity DataIC50: 165nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651827(CHEMBL5639354)
Affinity DataEC50:  195nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651830(CHEMBL5641920)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of IRAK1 (unknown origin) by Ambit kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed