Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50022296
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650461(CHEMBL5631094)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650457(CHEMBL5630267)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650462(CHEMBL5631151)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650467(CHEMBL5625055)
Affinity DataIC50: 0.930nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650466(CHEMBL5630624)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650464(CHEMBL5631037)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650465(CHEMBL5624545)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650459(CHEMBL5631065)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650460(CHEMBL5631083)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650469(CHEMBL5630714)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650463(CHEMBL5630609)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650468(CHEMBL5624580)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650456(CHEMBL5625037)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650461(CHEMBL5631094)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650457(CHEMBL5630267)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650461(CHEMBL5631094)
Affinity DataIC50: 11nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650462(CHEMBL5631151)
Affinity DataIC50: 15nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650463(CHEMBL5630609)
Affinity DataIC50: 16nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650459(CHEMBL5631065)
Affinity DataIC50: 17nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650456(CHEMBL5625037)
Affinity DataIC50: 21nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650458(CHEMBL5630498)
Affinity DataIC50: 22nMAssay Description:Inhibition of GST-tagged recombinant human EGFR T790M/L858R mutant (668 to 1210 residues) expressed in Insect cells incubated for 60 mins in presence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650460(CHEMBL5631083)
Affinity DataIC50: 26nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650466(CHEMBL5630624)
Affinity DataIC50: 47nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650465(CHEMBL5624545)
Affinity DataIC50: 49nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650464(CHEMBL5631037)
Affinity DataIC50: 50nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650467(CHEMBL5625055)
Affinity DataIC50: 65nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650468(CHEMBL5624580)
Affinity DataIC50: 83nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650469(CHEMBL5630714)
Affinity DataIC50: 212nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Puhe Biopharma

Curated by ChEMBL
LigandPNGBDBM50650458(CHEMBL5630498)
Affinity DataIC50: 963nMAssay Description:Inhibition of wildtype EGFR (unknown origin) incubated for 60 mins in presence of ATP by biochemical enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed