Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50022323
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataKd:  0.350nMAssay Description:Binding affinity to IRAK4 (unknown origin) by kinomescan competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM395297(N-{6-(2-Hydroxypropan-2-yl)-2-[2-(methylsulphonyl)...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726095(US20250074919, Example B36)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726075(US20250074919, Example B15)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726073(US20250074919, Example B13)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726074(US20250074919, Example B14)
Affinity DataIC50: 6nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726088(US20250074919, Example B29)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726092(US20250074919, Example B33)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 9nMAssay Description:Inhibition of CLK1 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726072(US20250074919, Example B12)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726076(US20250074919, Example B16)
Affinity DataIC50: 11nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 11nMAssay Description:Inhibition of FLT3 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726084(US20250074919, Example B24)
Affinity DataIC50: 11nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726083(US20250074919, Example B23)
Affinity DataIC50: 11nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataKd:  13nMAssay Description:Binding affinity to IRAK1 (unknown origin) by kinomescan competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726078(US20250074919, Example B18)
Affinity DataIC50: 22nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726080(US20250074919, Example B20)
Affinity DataIC50: 27nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 34nMAssay Description:Inhibition of DYRK1A (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650832(CHEMBL5632454)
Affinity DataIC50: 48nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726071(US20250074919, Example B11)
Affinity DataIC50: 51nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726081(US20250074919, Example B21)
Affinity DataIC50: 74nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650828(CHEMBL5633795)
Affinity DataIC50: 75nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650830(CHEMBL5631711)
Affinity DataIC50: 87nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650829(CHEMBL5633407)
Affinity DataIC50: 96nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650835(CHEMBL5631794)
Affinity DataIC50: 111nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650831(CHEMBL5631759)
Affinity DataIC50: 112nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50547964(CHEMBL4783351 | US20250074919, Example CA4948)
Affinity DataIC50: 115nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726089(US20250074919, Example B30)
Affinity DataIC50: 171nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726090(US20250074919, Example B31)
Affinity DataIC50: 178nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650833(CHEMBL5634060)
Affinity DataIC50: 194nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726093(US20250074919, Example B34)
Affinity DataIC50: 243nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM726082(US20250074919, Example B22)
Affinity DataIC50: 379nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 17A(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 788nMAssay Description:Inhibition of DRAK1 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650827(CHEMBL5633134)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 4.69E+3nMAssay Description:Inhibition of RIPK1 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650834(CHEMBL5633850)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of IRAK4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 8.35E+3nMAssay Description:Inhibition of RIPK2 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 38(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of NDR1 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of B-Raf (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of HIPK1 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of BTK (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit beta(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PKA-C beta (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ASK1 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PAK1 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CDK4/cyclinD3 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CaMKI (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MAPKAP-K2 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50650836(CHEMBL5633185)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
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