Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50019883
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM418436(US10457677, Example 4 | US10745399, Example 4 | US...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of ATM (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM245474(US9428503, 1)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624159(CHEMBL5438394)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624162(CHEMBL5411336)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624166(CHEMBL5434323)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624172(CHEMBL5423087)
Affinity DataIC50: 1nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624161(CHEMBL5402194)
Affinity DataIC50: 1nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624180(CHEMBL5438262)
Affinity DataIC50: 1nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624174(CHEMBL5419324)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624173(CHEMBL5425392)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 2nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624157(CHEMBL5415162)
Affinity DataIC50: 2nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624163(CHEMBL5414867)
Affinity DataIC50: 2nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 2nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624156(CHEMBL5407799)
Affinity DataIC50: 2nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624175(CHEMBL5419474)
Affinity DataIC50: 3nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624176(CHEMBL5429982)
Affinity DataIC50: 3nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624165(CHEMBL5412929)
Affinity DataIC50: 3nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624155(CHEMBL5439932)
Affinity DataIC50: 3nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50378201(CHEMBL4159350)
Affinity DataIC50: 3nMAssay Description:Inhibition of ATM (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624181(CHEMBL5406188)
Affinity DataIC50: 4nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50459007(CHEMBL4218734)
Affinity DataIC50: 4nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624179(CHEMBL5412263)
Affinity DataIC50: 5nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624154(CHEMBL5400114)
Affinity DataIC50: 6nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 7nMAssay Description:Inhibition of flag tagged- ATM (unknown origin) expressed in Escherichia coli BL21 incubated for 20 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624160(CHEMBL5416391)
Affinity DataIC50: 8nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624164(CHEMBL5437395)
Affinity DataIC50: 8nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624177(CHEMBL5398961)
Affinity DataIC50: 9nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624171(CHEMBL5418386)
Affinity DataIC50: 10nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ATR in human HCT-116 cells measured after 1 hr by Bradford assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)
Affinity DataIC50: 10nMAssay Description:Inhibition of DNA-PK in human HCT-116 cells measured after 1 hr by Bradford assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTarget of rapamycin complex subunit LST8(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human mTORC1 incubated for 90 mins by Lanthascreen time-resolved FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624158(CHEMBL5440952)
Affinity DataIC50: 13nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50208517(KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...)
Affinity DataIC50: 13nMAssay Description:Inhibition of ATM (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 14nMAssay Description:Inhibition of flag tagged- ATR (unknown origin) expressed in Escherichia coli BL21 incubated for 20 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624178(CHEMBL5439397)
Affinity DataIC50: 16nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 21nMAssay Description:Inhibition of flag tagged- ATR (unknown origin) expressed in Escherichia coli BL21 incubated for 20 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624169(CHEMBL5409082)
Affinity DataIC50: 22nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624168(CHEMBL5413082)
Affinity DataIC50: 26nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624167(CHEMBL5427955)
Affinity DataIC50: 30nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624170(CHEMBL5425985)
Affinity DataIC50: 31nMAssay Description:Inhibition of ATM (unknown origin) preincubated with compound for 30 mins followed by substrate addition and measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 36nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 170nMAssay Description:Inhibition of PIK3alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50624174(CHEMBL5419324)
Affinity DataIC50: 420nMAssay Description:Inhibition of DNA-PK (unknown origin) in presence of [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50: 545nMAssay Description:Inhibition of flag tagged- ATM (unknown origin) expressed in Escherichia coli BL21 incubated for 20 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed