Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50019889
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624231(CHEMBL5422297)
Affinity DataIC50: 120nMAssay Description:Inhibition of GPX4 (unknown origin) incubated for 1 hrs in presence of glutathione and glutathione reductase by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624232(CHEMBL5415644)
Affinity DataIC50: 130nMAssay Description:Inhibition of GPX4 (unknown origin) incubated for 1 hrs in presence of glutathione and glutathione reductase by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624232(CHEMBL5415644)
Affinity DataKi:  590nMAssay Description:Covalent inhibition of GPX4 (unknown origin) assessed as inhibition constant incubated for 30 to 90 mins in presence of glutathione, glutathione redu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624231(CHEMBL5422297)
Affinity DataKi:  630nMAssay Description:Covalent inhibition of GPX4 (unknown origin) assessed as inhibition constant incubated for 30 to 90 mins in presence of glutathione, glutathione redu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM66431(2-(3-chloro-N-(2-chloroacetyl)-4-methoxyanilino)-N...)
Affinity DataIC50: 4.85E+3nMAssay Description:Inhibition of GPX4 (unknown origin) incubated for 1 hrs in presence of glutathione and glutathione reductase by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50547192(CHEMBL4747331)
Affinity DataIC50: 8.42E+3nMAssay Description:Inhibition of GPX4 (unknown origin) incubated for 1 hrs in presence of glutathione and glutathione reductase by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM66431(2-(3-chloro-N-(2-chloroacetyl)-4-methoxyanilino)-N...)
Affinity DataKi:  2.89E+4nMAssay Description:Covalent inhibition of GPX4 (unknown origin) assessed as inhibition constant incubated for 30 to 90 mins in presence of glutathione, glutathione redu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed