Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50020188
TargetSodium channel protein type 9 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627165(CHEMBL5394673)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human Nav 1.7 expressed in HEK293T cells assessed as phasic block at 10 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627165(CHEMBL5394673)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as phasic block at 10 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM30705(SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human Nav 1.7 expressed in HEK293T cells assessed as phasic block at 10 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium channel protein type 9 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627166(CHEMBL5434746)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human Nav 1.7 expressed in HEK293T cells assessed as phasic block at 10 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM30705(SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as phasic block at 10 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627165(CHEMBL5394673)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of human Nav 1.7 expressed in HEK293T cells assessed as tonic block at 0.1 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50002341(CHEMBL442384)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as phasic block at 10 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM30705(SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of human Nav 1.7 expressed in HEK293T cells assessed as tonic block at 0.1 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50002341(CHEMBL442384)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as tonic block at 0.1 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627166(CHEMBL5434746)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as phasic block at 10 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM30705(SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as tonic block at 0.1 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627164(CHEMBL97407)
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as phasic block at 10 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627165(CHEMBL5394673)
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as tonic block at 0.1 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627166(CHEMBL5434746)
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of human Nav 1.7 expressed in HEK293T cells assessed as tonic block at 0.1 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627164(CHEMBL97407)
Affinity DataIC50: 1.18E+5nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as tonic block at 0.1 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627166(CHEMBL5434746)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as tonic block at 0.1 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed