Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50022343
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50291665(CHEMBL4165327)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataIC50: 22nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataIC50: 25nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651077(CHEMBL5631356)
Affinity DataKi:  26nMAssay Description:Non-competitive inhibition of electric eel AChE by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataIC50: 29nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataIC50: 31nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651077(CHEMBL5631356)
Affinity DataIC50: 86nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50651077(CHEMBL5631356)
Affinity DataIC50: 92nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50651078(CHEMBL5633239)
Affinity DataIC50: 133nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651078(CHEMBL5633239)
Affinity DataIC50: 135nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651079(CHEMBL5632891)
Affinity DataIC50: 194nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 340nMAssay Description:Antagonist activity at GluN2B NMDA receptor (unknown origin) assessed as inhibition of channel currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651080(CHEMBL5632465)
Affinity DataIC50: 340nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651076(CHEMBL5631365)
Affinity DataIC50: 360nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50651083(CHEMBL5633979)
Affinity DataIC50: 470nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651070(CHEMBL5629932)
Affinity DataIC50: 550nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651071(CHEMBL5633087)
Affinity DataIC50: 607nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50651070(CHEMBL5629932)
Affinity DataIC50: 621nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50062599(CHEMBL807 | Namenda | 3,5-Dimethyl-adamantan-1-yla...)
Affinity DataIC50: 780nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651081(CHEMBL5633141)
Affinity DataIC50: 799nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50651071(CHEMBL5633087)
Affinity DataIC50: 927nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataIC50: 941nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651073(CHEMBL5632160)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651069(CHEMBL5631752)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651074(CHEMBL5632181)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651082(CHEMBL5632076)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651072(CHEMBL5632219)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651077(CHEMBL5631356)
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651079(CHEMBL5632891)
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651078(CHEMBL5633239)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50651075(CHEMBL5631427)
Affinity DataIC50: 4.64E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651076(CHEMBL5631365)
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651080(CHEMBL5632465)
Affinity DataIC50: 6.04E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50536287(CHEMBL4581664)
Affinity DataIC50: 7.23E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50072951(CHEMBL3410478)
Affinity DataIC50: 7.31E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651081(CHEMBL5633141)
Affinity DataIC50: 7.83E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651082(CHEMBL5632076)
Affinity DataIC50: 9.54E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651072(CHEMBL5632219)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651069(CHEMBL5631752)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651074(CHEMBL5632181)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651071(CHEMBL5633087)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651070(CHEMBL5629932)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651075(CHEMBL5631427)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50651073(CHEMBL5632160)
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 1.46E+5nMAssay Description:Antagonist activity at GluN2A NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed