Compile Data Set for Download or QSAR
Report error Found 114 Enz. Inhib. hit(s) with all data for entry = 50019303
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617882(CHEMBL5436665)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617886(CHEMBL5394415)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617883(CHEMBL5393913)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617886(CHEMBL5394415)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617890(CHEMBL5404635)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617887(CHEMBL5420271)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617893(CHEMBL5394400)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617894(CHEMBL5430571)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617896(CHEMBL5441015)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617880(CHEMBL5437260)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617883(CHEMBL5393913)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617884(CHEMBL5429138)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617881(CHEMBL5399463)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617885(CHEMBL5426549)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617887(CHEMBL5420271)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617884(CHEMBL5429138)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617890(CHEMBL5404635)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617894(CHEMBL5430571)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM144315(US8969336, 577 | US8969336, 547 | Gilteritinib | U...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617896(CHEMBL5441015)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617874(CHEMBL5412366)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617874(CHEMBL5412366)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617879(CHEMBL5416037)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617878(CHEMBL5438877)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617874(CHEMBL5412366)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in Sf9 insect cells using histone H1 and ATP as substrate in presence of [gamma-33P]ATP as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617893(CHEMBL5394400)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617882(CHEMBL5436665)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617880(CHEMBL5437260)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617875(CHEMBL5421975)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617882(CHEMBL5436665)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human FLT3-ITD-F691L mutant expressed in Sf9 insect cells using myelin basic protein and ATP as substrate in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617888(CHEMBL5415809)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617877(CHEMBL5435762)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617878(CHEMBL5438877)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in Sf9 insect cells using histone H1 and ATP as substrate in presence of [gamma-33P]ATP as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617878(CHEMBL5438877)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617875(CHEMBL5421975)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617885(CHEMBL5426549)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617876(CHEMBL5416952)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617877(CHEMBL5435762)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617879(CHEMBL5416037)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617881(CHEMBL5399463)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM144315(US8969336, 577 | US8969336, 547 | Gilteritinib | U...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human FLT3-ITD-F691L mutant expressed in Sf9 insect cells using myelin basic protein and ATP as substrate in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617888(CHEMBL5415809)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617880(CHEMBL5437260)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in Sf9 insect cells using histone H1 and ATP as substrate in presence of [gamma-33P]ATP as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM144315(US8969336, 577 | US8969336, 547 | Gilteritinib | U...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617876(CHEMBL5416952)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617889(CHEMBL5398078)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human FLT3-ITD mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617897(CHEMBL5412888)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617889(CHEMBL5398078)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human FLT3-D835Y mutant expressed in Sf9 insect cells using AGLT peptide and ATP as substrate in presence of [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617894(CHEMBL5430571)
Affinity DataIC50: 31nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in Sf9 insect cells using histone H1 and ATP as substrate in presence of [gamma-33P]ATP as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
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