Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50022405
LigandPNGBDBM50651871(CHEMBL5641637)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human PDE9A2 expressed in Sf9 cells using cGMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50651870(CHEMBL5641902)
Affinity DataIC50: 2nMAssay Description:Inhibition of PDE9A (unknown origin) by high-throughput screening analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM477941(US10889591, Compound 25 | 2-oxo-4-(6-azaspiro[2.5]...)
Affinity DataIC50: 3nMAssay Description:Inhibition of PDE9A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM224783(US9328120, 13)
Affinity DataIC50: 4nMAssay Description:Inhibition of human PDE9A2 expressed in Sf9 cells using cGMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50651869(CHEMBL5647664)
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50397838(CHEMBL2179105 | US10513524, Reference compound dis...)
Affinity DataIC50: 8nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50407400(CHEMBL5285855)
Affinity DataIC50: 11nMAssay Description:Inhibition of PDE9A (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50606804(CHEMBL5221005)
Affinity DataIC50: 17nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50398799(CHEMBL2180070)
Affinity DataIC50: 32nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50513227(CHEMBL4547969)
Affinity DataIC50: 34nMAssay Description:Inhibition of PDE9A (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM50597848(CHEMBL5205841)
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50651868(CHEMBL5639215)
Affinity DataIC50: 52nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50543968(CHEMBL4636079)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells assessed as inhibition of breakdown of cGMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50540047(CHEMBL4644938)
Affinity DataIC50: 58nMAssay Description:Inhibition of PDE9A (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50457396(CHEMBL4206492)
Affinity DataIC50: 69nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50540047(CHEMBL4644938)
Affinity DataIC50: 80nMAssay Description:Inhibition of PDE1B2 (10 to 487 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50651873(CHEMBL5646643)
Affinity DataIC50: 99nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50318484(CHEMBL190461 | 2-((1R,6R)-6-Isopropenyl-3-methyl-c...)
Affinity DataIC50: 110nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50651872(CHEMBL5647316)
Affinity DataIC50: 223nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50407400(CHEMBL5285855)
Affinity DataIC50: 366nMAssay Description:Inhibition of PDE5A1 (535 to 860 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649088(CHEMBL3943305)
Affinity DataIC50: 526nMAssay Description:Inhibition of PDE1C (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50407400(CHEMBL5285855)
Affinity DataIC50: 554nMAssay Description:Inhibition of PDE1B2 (10 to 487 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50540047(CHEMBL4644938)
Affinity DataIC50: 787nMAssay Description:Inhibition of PDE5A1 (535 to 860 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50398799(CHEMBL2180070)
Affinity DataIC50: 900nMAssay Description:Inhibition of PDE1C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCholinesterase(Horse)TBA
LigandPNGBDBM50606804(CHEMBL5221005)
Affinity DataIC50: 960nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50543968(CHEMBL4636079)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant PDE1C expressed in Sf9 cells assessed as inhibition of breakdown of cGMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50651865(CHEMBL5639849)
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50027176(CHEBI:34795 | 2-Acetoxy-Benzoic Acid | 3-Isobutyl-...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of PDE3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50651867(CHEMBL5647056)
Affinity DataIC50: 8.21E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM131008(US8829000, 70)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50651866(CHEMBL5646392)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50027176(CHEBI:34795 | 2-Acetoxy-Benzoic Acid | 3-Isobutyl-...)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50027176(CHEBI:34795 | 2-Acetoxy-Benzoic Acid | 3-Isobutyl-...)
Affinity DataIC50: 3.17E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50027176(CHEBI:34795 | 2-Acetoxy-Benzoic Acid | 3-Isobutyl-...)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of full-length PDE9A1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed