Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50021665
TargetHistone deacetylase 8(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50643277(CHEMBL5569561)
Affinity DataIC50: 53nMAssay Description:Inhibition of HDAC8 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate measured after 30 mins by fluorescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM468609(US10807944, Compound RLS3-43 | US10870618, Compoun...)
Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM468609(US10807944, Compound RLS3-43 | US10870618, Compoun...)
Affinity DataIC50: 90nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50643276(CHEMBL5571601)
Affinity DataIC50: 372nMAssay Description:Inhibition of HDAC8 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate measured after 30 mins by fluorescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM468609(US10807944, Compound RLS3-43 | US10870618, Compoun...)
Affinity DataIC50: 800nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM468609(US10807944, Compound RLS3-43 | US10870618, Compoun...)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed