Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50022368
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of KAT6A (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of KAT6A (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of KAT6A (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT7(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant human KAT7 catalytic domain using H3 peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6B(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of full length recombinant human KAT6B catalytic domain using H4 peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid sci...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT7(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant human KAT7 catalytic domain using H3 peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT5(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of full length recombinant human KAT5 catalytic domain using H2A peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid sci...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT5(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of full length recombinant human KAT5 catalytic domain using H2A peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid sci...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of full length recombinant human KAT8 catalytic domain using H4 peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid scin...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 5.61E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 5.63E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 6.53E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 6.71E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 6.72E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 7.13E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 7.33E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6B(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of full length recombinant human KAT6B catalytic domain using H4 peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid sci...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 8.44E+3nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT8(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length recombinant human KAT8 catalytic domain using H4 peptide and [3H]-acetyl-coA as substrate incubated for 1 hr by liquid scin...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A(Human)
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Children's Hospital Affiliated to Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of recombinant human KAT6A catalytic domain using [3H]-acetyl-coA as substrate pretreated with compound for 20 mins followed by substrate ...More data for this Ligand-Target Pair















3D Structure (crystal)









