Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50022425
TargetBeta-secretase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50031615(CHEMBL3359762)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50369721(CHEMBL3702836)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50239954(CHEMBL4080520)
Affinity DataKi:  2.70nMAssay Description:Binding affinity to full length human recombinant MMP-13 using Mca-PLGL-Dpa-AR-NH2 as fluorogenic peptide substrate assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBeta-secretase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50031616(CHEMBL3359761)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBeta-secretase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50031616(CHEMBL3359761)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBeta-secretase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50031615(CHEMBL3359762)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50652124(CHEMBL5641567)
Affinity DataKi:  10nMAssay Description:Binding affinity to full length human recombinant MMP-13 using Mca-PLGL-Dpa-AR-NH2 as fluorogenic peptide substrate assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50652123(CHEMBL5646917)
Affinity DataKi:  12nMAssay Description:Binding affinity to full length human recombinant MMP-13 using Mca-PLGL-Dpa-AR-NH2 as fluorogenic peptide substrate assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50652126(CHEMBL4114685)
Affinity DataIC50: 16nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50652122(CHEMBL5647478)
Affinity DataIC50: 17nMAssay Description:Inhibition of Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein delta homolog 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50059215(CHEMBL3393328)
Affinity DataKi:  25nMAssay Description:Binding affinity to DLK (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDevelopmentally-regulated GTP-binding protein 1(Homo sapiens)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50059215(CHEMBL3393328)
Affinity DataIC50: 180nMAssay Description:Inhibition of DRG1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50652125(CHEMBL5639382)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed