Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50020340
LigandChemical structure of BindingDB Monomer ID 247150BDBM247150(US9701672, 4 | (S,E)-2-Methyl-N-(2,2,2-trifluoro-1...)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 247150BDBM247150(US9701672, 4 | (S,E)-2-Methyl-N-(2,2,2-trifluoro-1...)
Affinity DataIC50: 0.760nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 253621BDBM253621(US9701672, 52)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50518069BDBM50518069(CHEMBL4542050 | US11479538, Example 22)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 253628BDBM253628(US9701672, 59)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 253628BDBM253628(US9701672, 59)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629067BDBM50629067(CHEMBL5416977)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629063BDBM50629063(CHEMBL5398266)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629067BDBM50629067(CHEMBL5416977)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50518069BDBM50518069(CHEMBL4542050 | US11479538, Example 22)
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 253621BDBM253621(US9701672, 52)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 201232BDBM201232(US9187424, 2-1 | US9187424, 2)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 249799BDBM249799(US9701672, 38)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 578481BDBM578481((S)-3-(5-Oxo-4,5-dihydro-1H-tetrazol-1-yl)-4-(p-to...)
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629066BDBM50629066(CHEMBL5424825)
Affinity DataIC50: 14nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 201232BDBM201232(US9187424, 2-1 | US9187424, 2)
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 20nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 578481BDBM578481((S)-3-(5-Oxo-4,5-dihydro-1H-tetrazol-1-yl)-4-(p-to...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629063BDBM50629063(CHEMBL5398266)
Affinity DataIC50: 34nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 249535BDBM249535(US9701672, 36 | US9701672, 37)
Affinity DataIC50: 36nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 249799BDBM249799(US9701672, 38)
Affinity DataIC50: 37nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 249535BDBM249535(US9701672, 36 | US9701672, 37)
Affinity DataIC50: 57nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629066BDBM50629066(CHEMBL5424825)
Affinity DataIC50: 77nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629064BDBM50629064(CHEMBL5411387)
Affinity DataIC50: 433nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629063BDBM50629063(CHEMBL5398266)
Affinity DataEC50:  608nMAssay Description:Transactivation of PXR in human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as increase in luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629065BDBM50629065(CHEMBL5412270)
Affinity DataIC50: 704nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629064BDBM50629064(CHEMBL5411387)
Affinity DataEC50:  845nMAssay Description:Transactivation of PXR in human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as increase in luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629066BDBM50629066(CHEMBL5424825)
Affinity DataEC50:  1.54E+3nMAssay Description:Transactivation of PXR in human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as increase in luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629064BDBM50629064(CHEMBL5411387)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50629065BDBM50629065(CHEMBL5412270)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant human MGAT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 578481BDBM578481((S)-3-(5-Oxo-4,5-dihydro-1H-tetrazol-1-yl)-4-(p-to...)
Affinity DataEC50: >2.90E+4nMAssay Description:Transactivation of PXR in human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as increase in luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human MGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human DGAT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human DC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human ACAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human AWAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human AWAT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetyl-CoA acetyltransferase, cytosolic(Homo sapiens)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 289003BDBM289003(US10093650, Example 16 | US10093650, Example 14 | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human ACAT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 201232BDBM201232(US9187424, 2-1 | US9187424, 2)
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of PXR in human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as increase in luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed