Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50020351
LigandPNGBDBM370121(6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcy...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629187(CHEMBL5402601)
Affinity DataKi:  0.130nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50021718(CHEMBL3298678)
Affinity DataKi:  0.150nMAssay Description:Binding affinity to ERK2 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629190(CHEMBL5434470)
Affinity DataKi:  0.160nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50629183(CHEMBL5428299)
Affinity DataKi:  0.170nMAssay Description:Binding affinity to ERK2 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629186(CHEMBL5434780)
Affinity DataKi:  0.170nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629188(CHEMBL5405526)
Affinity DataKi:  0.180nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629201(CHEMBL5422841)
Affinity DataKi:  0.180nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629196(CHEMBL5423838)
Affinity DataKi:  0.180nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629198(CHEMBL5399918)
Affinity DataKi:  0.210nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50629182(CHEMBL5399703)
Affinity DataKi:  0.220nMAssay Description:Binding affinity to ERK2 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629189(CHEMBL5415273)
Affinity DataKi:  0.340nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM236877(US9388171, I-5)
Affinity DataKi:  0.360nMAssay Description:Binding affinity to ERK2 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629199(CHEMBL5425198)
Affinity DataKi:  0.440nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629193(CHEMBL5422107)
Affinity DataKi:  0.490nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629194(CHEMBL5398255)
Affinity DataKi:  0.630nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629200(CHEMBL5402758)
Affinity DataKi:  1nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629195(CHEMBL5433947)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629181(CHEMBL5408374)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM498185(US11014911, Example 13 | US11718603, Example 13 | ...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629197(CHEMBL5429216)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM106950(US8592581, 1 | US20250197425, Comparative A2)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629183(CHEMBL5428299)
Affinity DataKi:  6.5nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629182(CHEMBL5399703)
Affinity DataKi:  7.90nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629192(CHEMBL5440034)
Affinity DataKi:  8.70nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629184(CHEMBL5403871)
Affinity DataKi:  9nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM236877(US9388171, I-5)
Affinity DataKi:  11nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629177(CHEMBL5401047)
Affinity DataKi:  13nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50021718(CHEMBL3298678)
Affinity DataKi:  16nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629191(CHEMBL5427628)
Affinity DataKi:  17nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629185(CHEMBL5409832)
Affinity DataKi:  71nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629178(CHEMBL5404558)
Affinity DataKi:  88nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629180(CHEMBL5438013)
Affinity DataKi:  240nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629176(CHEMBL5403389)
Affinity DataKi:  750nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629179(CHEMBL5428634)
Affinity DataKi:  920nMAssay Description:Binding affinity to CDK2/Cyclin E1 (unknown origin) using Ulight-MBP as substrate assessed as inhibition constant preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed