Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50022432
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652202(CHEMBL5641539)
Affinity DataIC50: 4nMAssay Description:Inhibition of EGFR del19/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652204(CHEMBL5646626)
Affinity DataIC50: 4nMAssay Description:Inhibition of EGFR del19/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652205(CHEMBL5646609)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of EGFR del19/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652205(CHEMBL5646609)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652204(CHEMBL5646626)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652205(CHEMBL5646609)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of EGFR phosphorylation in human PC-9 cells harboring Del19/T790M/C797S mutant incubated for 6 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652203(CHEMBL5641915)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of EGFR del19/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652203(CHEMBL5641915)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of EGFR phosphorylation in human PC-9 cells harboring Del19/T790M/C797S mutant incubated for 6 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652203(CHEMBL5641915)
Affinity DataIC50: 13nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652202(CHEMBL5641539)
Affinity DataIC50: 20nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 21nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 55nMAssay Description:Inhibition of EGFR del19/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 188nMAssay Description:Inhibition of EGFR phosphorylation in human PC-9 cells harboring Del19/T790M/C797S mutant incubated for 6 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652205(CHEMBL5646609)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of EGFR phosphorylation in human A-431 cells harboring wild type EGFR incubated for 6 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652203(CHEMBL5641915)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of EGFR phosphorylation in human A-431 cells harboring wild type EGFR incubated for 6 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652202(CHEMBL5641539)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of EGFR phosphorylation in human A-431 cells harboring wild type EGFR incubated for 6 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652204(CHEMBL5646626)
Affinity DataIC50: 4.58E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652203(CHEMBL5641915)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type EGFR (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652205(CHEMBL5646609)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of wild type EGFR (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed