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Report error Found 225 Enz. Inhib. hit(s) with all data for entry = 50035604
LigandPNGBDBM50025450(CHEMBL1790294 | Sodium; 1,4a,6a-trimethyl-2-oxo-he...)
Affinity DataKi:  1.70nMAssay Description:Apparent inhibitory constant value for rat prostatic steroid 5-alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50213061(CHEMBL2298601)
Affinity DataKi:  5nMAssay Description:Apparent inhibitory constant value for rat prostatic steroid 5alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50367296(CHEMBL1790284)
Affinity DataKi:  6nMAssay Description:Apparent inhibitory constant value for rat prostatic steroid 5-alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50226049(CHEMBL3349139)
Affinity DataKi:  13nMAssay Description:Apparent inhibitory constant value for rat prostatic steroid 5-alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025400(1'-ethyl-4a',6a'-dimethylspiro[tetrahydrofuran-2,7...)
Affinity DataKi:  24nMAssay Description:Apparent inhibitory constant value for rat prostatic steroid 5-alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50216166(CHEMBL3349181)
Affinity DataKi:  29nMAssay Description:Apparent inhibitory constant value for rat prostatic steroid 5-alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50225982(CHEMBL3349117)
Affinity DataKi:  133nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025359(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f...)
Affinity DataKi:  165nMAssay Description:Apparent inhibitory constant value for rat prostatic 5-alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025367(4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]qu...)
Affinity DataIC50:  0.130nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50225985(CHEMBL3349105)
Affinity DataIC50:  0.210nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025454(1,4,4a,6a-Tetramethyl-2-oxo-hexadecahydro-indeno[5...)
Affinity DataIC50:  0.560nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025341(4a,6a-Dimethyl-7-(3-methyl-butyryl)-hexadecahydro-...)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAndrogen receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50025425(17-Hydroxy-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,...)
Affinity DataIC50:  1.5nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025450(CHEMBL1790294 | Sodium; 1,4a,6a-trimethyl-2-oxo-he...)
Affinity DataIC50:  1.70nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025332(1,4a,6a-Trimethyl-7-(2-methyl-butyryl)-hexadecahyd...)
Affinity DataIC50:  1.90nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAndrogen receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  2.20nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAndrogen receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50025417(7-Hydroxy-1,4a,6a-trimethyl-1,4a,4b,5,6,6a,7,8,9,9...)
Affinity DataIC50:  2.40nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025415(CHEMBL3349288 | N,N-Diethyl-2-(1,4a,6a-trimethyl-2...)
Affinity DataIC50:  2.5nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025353(7-(1-Hydroxy-ethyl)-1,4a,6a-trimethyl-hexadecahydr...)
Affinity DataIC50:  2.80nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAndrogen receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataIC50:  3.20nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50025375(7-Acetyl-1,4a,6a,8-tetramethyl-hexadecahydro-inden...)
Affinity DataIC50:  3.40nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025413(4-(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,...)
Affinity DataIC50:  3.40nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50405303(CHEMBL2021336)
Affinity DataIC50:  3.5nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025399(CHEMBL1790293 | Sodium; 4-(1,4a,6a-trimethyl-2-oxo...)
Affinity DataIC50:  3.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025337(7-(2-Hydroxy-1-methyl-ethyl)-1,4a,6a-trimethyl-hex...)
Affinity DataIC50:  3.80nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025379(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f...)
Affinity DataIC50:  4.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025330(1',4a',6a'-trimethylspiro[tetrahydrofuran-2,7'-per...)
Affinity DataIC50:  4.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025455(4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]qu...)
Affinity DataIC50:  6.30nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025395((1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-...)
Affinity DataIC50:  6.80nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  6.80nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAndrogen receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50025443(7-Hydroxy-1,4a,6a-trimethyl-1,3,4,4a,4b,5,6,6a,7,8...)
Affinity DataIC50:  7.40nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025359(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f...)
Affinity DataIC50:  7.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50367296(CHEMBL1790284)
Affinity DataIC50:  7.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025364(2-(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,...)
Affinity DataIC50:  7.60nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025447(CHEMBL3085570 | N,N-Diethyl-2-(1,4a,6a-trimethyl-2...)
Affinity DataIC50:  7.90nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50226049(CHEMBL3349139)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50213061(CHEMBL2298601)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50225983(CHEMBL3349111)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAndrogen receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50025385(Acetic acid 17-acetyl-10,13-dimethyl-6-methylene-3...)
Affinity DataIC50:  12nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025388(CHEMBL1790288 | N,N-Diethyl-2-(1,4a,6a-trimethyl-2...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025449(1,4a,6a-Trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAndrogen receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50025381(1,4a,6a-Trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b...)
Affinity DataIC50:  13nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025352(CHEMBL3349083 | Sodium; 2-(1,4a,6a-trimethyl-2-oxo...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAndrogen receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50025351(1,4a,6a-Trimethyl-7-(1H-pyrrole-2-carbonyl)-1,4a,4...)
Affinity DataIC50:  15nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025333(7-Acetyl-1,4a,6a,8-tetramethyl-hexadecahydro-inden...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50225996(CHEMBL3349104)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAndrogen receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50421737(CHEMBL2311174)
Affinity DataIC50:  19nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025371(7-(1-Hydroxy-ethyl)-1,4a,6a,8-tetramethyl-hexadeca...)
Affinity DataIC50:  19nMAssay Description:Inhibition of Steroid 5-alpha-reductase from rat prostateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50025372(4,10,13-Trimethyl-3-oxo-octadecahydro-4-aza-cyclop...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50226048(CHEMBL3349088)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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