Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50020381
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629475BDBM50629475(CHEMBL5410439)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629476BDBM50629476(CHEMBL5410299)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629474BDBM50629474(CHEMBL5436614)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524341BDBM524341(US11168082, Cpd. No. 37 | (R)-2-fluoro-4-(5-(1-met...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524327BDBM524327(US11168082, Cpd. No. 23 | (R)-2-fluoro-4-(5-(1-met...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524342BDBM524342(US11168082, Cpd. No. 38 | 2-fluoro-4-(5-(1-methyl-...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629470BDBM50629470(CHEMBL5405014)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524398BDBM524398(US11168082, Cpd. No. 97 | 4-(5-(1-methyl-1H-indazo...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524399BDBM524399(US11168082, Cpd. No. 98 | 4-(5-(4-methyl-3,4-dihyd...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629468BDBM50629468(CHEMBL5402939)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524385BDBM524385(US11168082, Cpd. No. 83 | 4-(5-(1-methyl-1H-indol-...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524387BDBM524387(US11168082, Cpd. No. 85 | 4-(5-(4-(dimethylamino)p...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524375BDBM524375(US11168082, Cpd. No. 73 | 4-(1-(4-aminobutyl)-5-(1...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524369BDBM524369(US11168082, Cpd. No. 67 | 4-(5-(1-methyl-1H-indazo...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629467BDBM50629467(CHEMBL5405687)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629462BDBM50629462(CHEMBL5399283)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524390BDBM524390(US11168082, Cpd. No. 89 | 3-fluoro-4-(5-(1-methyl-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629461BDBM50629461(CHEMBL5405194)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524400BDBM524400(US11168082, Cpd. No. 99 | 4-(5-(benzo[d][1,3]dioxo...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629463BDBM50629463(CHEMBL5421980)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590443BDBM50590443(Seclidemstat | Sp-2577 | SP-2577 | SP2577 | SECLID...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524374BDBM524374(US11168082, Cpd. No. 72 | 4-(1-(3-aminopropyl)-5-(...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629455BDBM50629455(CHEMBL5405326)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524376BDBM524376(US11168082, Cpd. No. 74 | 4-(5-(1-methyl-1H-indazo...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629456BDBM50629456(CHEMBL5396712)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524386BDBM524386(US11168082, Cpd. No. 84 | 4-(5-(4-(tert-butyl)phen...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629459BDBM50629459(CHEMBL5403000)
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629457BDBM50629457(CHEMBL5406073)
Affinity DataIC50: 59nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629464BDBM50629464(CHEMBL5427183)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524313BDBM524313(US11168082, Cpd. No. 9 | (R)-4-(1-(pyrrolidin-3-yl...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629466BDBM50629466(CHEMBL5417291)
Affinity DataIC50: 94nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629472BDBM50629472(CHEMBL5400159)
Affinity DataIC50: 121nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262048BDBM50262048(CHEMBL3134377)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629460BDBM50629460(CHEMBL5407075)
Affinity DataIC50: 146nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524384BDBM524384(US11168082, Cpd. No. 82 | 2-methyl-4-(5-(1-methyl-...)
Affinity DataIC50: 156nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524394BDBM524394(US11168082, Cpd. No. 93 | 3-methyl-4-(5-(1-methyl-...)
Affinity DataIC50: 215nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629473BDBM50629473(CHEMBL5422216)
Affinity DataIC50: 229nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629458BDBM50629458(CHEMBL5418187)
Affinity DataIC50: 354nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629465BDBM50629465(CHEMBL5406978)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629471BDBM50629471(CHEMBL5433815)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629469BDBM50629469(CHEMBL5399271)
Affinity DataIC50: 6.25E+3nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524350BDBM524350(US11168082, Cpd. No. 46 | 4-(1-((1H-imidazol-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524351BDBM524351(US11168082, Cpd. No. 47 | 2-fluoro-4-(5-(1-melhyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed