Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50022449
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652379(CHEMBL5646721)
Affinity DataIC50: 160nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652377(CHEMBL5639827)
Affinity DataIC50: 170nMAssay Description:Inhibition of human BuChE measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652377(CHEMBL5639827)
Affinity DataIC50: 170nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652377(CHEMBL5639827)
Affinity DataIC50: 210nMAssay Description:Inhibition of human GSK3beta by luminescent microplate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataIC50: 220nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652379(CHEMBL5646721)
Affinity DataIC50: 260nMAssay Description:Inhibition of human GSK3beta by luminescent microplate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652374(CHEMBL5177941)
Affinity DataIC50: 260nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652378(CHEMBL5639721)
Affinity DataIC50: 350nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652377(CHEMBL5639827)
Affinity DataIC50: 460nMAssay Description:Inhibition of self mediated Amyloid beta (1 to 42) (unknown origin) aggregation measured every 5 mins by ThT fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652380(CHEMBL5647222)
Affinity DataIC50: 630nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652379(CHEMBL5646721)
Affinity DataIC50: 690nMAssay Description:Inhibition of human BuChE measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652379(CHEMBL5646721)
Affinity DataIC50: 770nMAssay Description:Inhibition of self mediated Amyloid beta (1 to 42) (unknown origin) aggregation measured every 5 mins by ThT fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652375(CHEMBL5647393)
Affinity DataIC50: 810nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652381(CHEMBL5647318)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human GSK3beta by luminescent microplate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50342600(RIVASTIGMINE)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human BuChE measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652372(CHEMBL5639262)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652369(CHEMBL5647144)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of human BuChE measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652373(CHEMBL5647220)
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50605099(CHEMBL5189796)
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652376(CHEMBL5639307)
Affinity DataIC50: 6.01E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652371(CHEMBL5647542)
Affinity DataIC50: 9.63E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652377(CHEMBL5639827)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human tau protein aggregation incubated for 1.5 hrs by TMB substrate based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652379(CHEMBL5646721)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of human tau protein aggregation incubated for 1.5 hrs by TMB substrate based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652370(CHEMBL5200613)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataIC50: 8.74E+4nMAssay Description:Inhibition of self mediated Amyloid beta (1 to 42) (unknown origin) aggregation measured every 5 mins by ThT fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed