Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50020853
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50384789(CHEMBL2037378 | Laccaic acid A (LCA))
Affinity DataKi:  300nMAssay Description:Competitive inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50634146(CHEMBL5440205)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIV-1 RNase H activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50634145(CHEMBL5407832)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIV-1 RNase H activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50634143(CHEMBL5413305)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of HIV-1 RNase H using 5'-GAUCUGAGCCUGGGAGCU-3'-FAM RNA/BHQ-5'-AGCTCCCAGGCTCAGATC-3' DNA as substrate measured after 60 mins by FRET analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50634144(CHEMBL5416177)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of HIV-1 RNase H using 5'-GAUCUGAGCCUGGGAGCU-3'-FAM RNA/BHQ-5'-AGCTCCCAGGCTCAGATC-3' DNA as substrate measured after 60 mins by FRET analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50384789(CHEMBL2037378 | Laccaic acid A (LCA))
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of HIV-1 RNase H using 5'-GAUCUGAGCCUGGGAGCU-3'-FAM RNA/BHQ-5'-AGCTCCCAGGCTCAGATC-3' DNA as substrate measured after 60 mins by FRET analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed