Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50020502
TargetHistone deacetylase 6(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630612BDBM50630612(CHEMBL5424460)
Affinity DataEC50:  5.80nMAssay Description:Protac activity at HDAC6 in human MM1.S cells assessed as HDAC6 protein degradation incubated for 24 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602361BDBM50602361(CHEMBL5206304)
Affinity DataEC50:  6.5nMAssay Description:Protac activity at HDAC6 in human MM1.S cells assessed as HDAC6 protein degradation incubated for 24 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630608BDBM50630608(CHEMBL5415637)
Affinity DataKi:  430nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 65456BDBM65456(pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...)
Affinity DataKi:  3.30E+3nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630606BDBM50630606(CHEMBL5414951)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630607BDBM50630607(CHEMBL5427990)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 65454BDBM65454(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Affinity DataKi:  6.40E+3nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630600BDBM50630600(CHEMBL5441135)
Affinity DataKi:  6.80E+3nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630608BDBM50630608(CHEMBL5415637)
Affinity DataIC50: 7.40E+3nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630599BDBM50630599(CHEMBL5405986 | US20250127903, Compound 107)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 65456BDBM65456(pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...)
Affinity DataIC50: 1.30E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630607BDBM50630607(CHEMBL5427990)
Affinity DataIC50: 1.40E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630611BDBM50630611(CHEMBL5414968)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630606BDBM50630606(CHEMBL5414951)
Affinity DataIC50: 1.60E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 65454BDBM65454(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Affinity DataIC50: 1.90E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630600BDBM50630600(CHEMBL5441135)
Affinity DataIC50: 2.00E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630603BDBM50630603(CHEMBL5430307)
Affinity DataKi:  2.50E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630596BDBM50630596(CHEMBL5405702)
Affinity DataKi:  2.80E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630599BDBM50630599(CHEMBL5405986 | US20250127903, Compound 107)
Affinity DataIC50: 2.80E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630593BDBM50630593(CHEMBL5410980)
Affinity DataKi:  2.90E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630602BDBM50630602(CHEMBL5416921)
Affinity DataKi:  2.90E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630589BDBM50630589(CHEMBL5437759)
Affinity DataKi:  3.00E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630604BDBM50630604(CHEMBL5421440)
Affinity DataKi:  3.10E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630594BDBM50630594(CHEMBL5399110)
Affinity DataKi:  3.50E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630605BDBM50630605(CHEMBL5435181)
Affinity DataKi:  3.50E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630611BDBM50630611(CHEMBL5414968)
Affinity DataIC50: 3.60E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630592BDBM50630592(CHEMBL5424655)
Affinity DataKi:  4.10E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630597BDBM50630597(CHEMBL5404650)
Affinity DataKi:  4.20E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630601BDBM50630601(CHEMBL5403248)
Affinity DataKi:  4.40E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630591BDBM50630591(CHEMBL5411174)
Affinity DataKi:  4.50E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630590BDBM50630590(CHEMBL5398662)
Affinity DataKi:  5.30E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630603BDBM50630603(CHEMBL5430307)
Affinity DataIC50: 5.50E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630595BDBM50630595(CHEMBL5439012)
Affinity DataKi:  5.60E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630596BDBM50630596(CHEMBL5405702)
Affinity DataIC50: 6.00E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630602BDBM50630602(CHEMBL5416921)
Affinity DataIC50: 6.20E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630593BDBM50630593(CHEMBL5410980)
Affinity DataIC50: 6.30E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 631083BDBM631083(US11802131, Example 10 | N-(2,6-dioxo-3-piperidyl)...)
Affinity DataKi:  6.30E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630604BDBM50630604(CHEMBL5421440)
Affinity DataIC50: 6.50E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630610BDBM50630610(CHEMBL5420119)
Affinity DataKi:  6.50E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630589BDBM50630589(CHEMBL5437759)
Affinity DataIC50: 6.50E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630598BDBM50630598(CHEMBL5419302)
Affinity DataKi:  6.50E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630609BDBM50630609(CHEMBL5410366)
Affinity DataKi:  6.60E+4nMAssay Description:Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630594BDBM50630594(CHEMBL5399110)
Affinity DataIC50: 7.40E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630605BDBM50630605(CHEMBL5435181)
Affinity DataIC50: 7.50E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630592BDBM50630592(CHEMBL5424655)
Affinity DataIC50: 8.60E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630597BDBM50630597(CHEMBL5404650)
Affinity DataIC50: 8.70E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630601BDBM50630601(CHEMBL5403248)
Affinity DataIC50: 9.00E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630591BDBM50630591(CHEMBL5411174)
Affinity DataIC50: 9.30E+4nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630590BDBM50630590(CHEMBL5398662)
Affinity DataIC50: 1.07E+5nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630595BDBM50630595(CHEMBL5439012)
Affinity DataIC50: 1.14E+5nMAssay Description:Binding affinity to human CRBN TBD using BODIPY-uracil as substrate by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
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