Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50021581
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50485492(Grazoprevir | Grazoprevir monohydrate | MK-5172 | ...)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of Hepatitis C virus NS3-4A protease genotype 1aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50485492(Grazoprevir | Grazoprevir monohydrate | MK-5172 | ...)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of Hepatitis C virus NS3-4A protease genotype 1bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50485492(Grazoprevir | Grazoprevir monohydrate | MK-5172 | ...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of Hepatitis C virus NS3-4A protease genotype 2aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50485492(Grazoprevir | Grazoprevir monohydrate | MK-5172 | ...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of Hepatitis C virus NS3-4A protease genotype 2bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50642153(ITMN-191 | R-7227 | R7227 | RO-5190591-001 | RO519...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Hepatitis C virus genotype 4 NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50642153(ITMN-191 | R-7227 | R7227 | RO-5190591-001 | RO519...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50642153(ITMN-191 | R-7227 | R7227 | RO-5190591-001 | RO519...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Hepatitis C virus genotype 6 NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50642153(ITMN-191 | R-7227 | R7227 | RO-5190591-001 | RO519...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Hepatitis C virus genotype 5 NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50642153(ITMN-191 | R-7227 | R7227 | RO-5190591-001 | RO519...)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of Hepatitis C virus genotype 3a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50642154(Simeprevir sodium | TMC-435 SODIUM SALT | Olysio)
Affinity DataKi:  0.360nMAssay Description:Binding affinity to Hepatitis C virus genotype 4 NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50642154(Simeprevir sodium | TMC-435 SODIUM SALT | Olysio)
Affinity DataKi:  0.360nMAssay Description:Binding affinity to Hepatitis C virus genotype 1 NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50485492(Grazoprevir | Grazoprevir monohydrate | MK-5172 | ...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of Hepatitis C virus NS3-4A protease genotype 3aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50642153(ITMN-191 | R-7227 | R7227 | RO-5190591-001 | RO519...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Hepatitis C virus genotype 2b NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50531952(Elbasvir | MK-8742)
Affinity DataEC50:  3nMAssay Description:Inhibition of Hepatitis C virus genotype 2a NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50531952(Elbasvir | MK-8742)
Affinity DataEC50:  3nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50642153(ITMN-191 | R-7227 | R7227 | RO-5190591-001 | RO519...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Hepatitis C virus genotype 3a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50531952(Elbasvir | MK-8742)
Affinity DataEC50:  4nMAssay Description:Inhibition of Hepatitis C virus genotype 1a NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50326056((1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazin...)
Affinity DataKi:  7nMAssay Description:Binding affinity to Hepatitis C virus genotype 1H NS3-4A protease assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA polymerase subunit gamma-1(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50248359(Adefovir dipivoxil | GS-0840 | Hepsera)
Affinity DataKi:  970nMAssay Description:Binding affinity to human DNA polymerase gamma assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50248359(Adefovir dipivoxil | GS-0840 | Hepsera)
Affinity DataKi:  1.18E+3nMAssay Description:Binding affinity to DNA polymerase alpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50642153(ITMN-191 | R-7227 | R7227 | RO-5190591-001 | RO519...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Hepatitis C virus genotype 1a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed