Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50021406
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate preincubated with compound for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50640306(CHEMBL5570344)
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-LOX in human Neutrophil using arachidonic acid as substrate preincubated with compound for 15 mins followed by substrate and A23187 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50640308(CHEMBL2005058)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-LOX in human Neutrophil using arachidonic acid as substrate preincubated with compound for 15 mins followed by substrate and A23187 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50640308(CHEMBL2005058)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate preincubated with compound for 15 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50640307(CHEMBL5566074)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 5-LOX in human Neutrophil preincubated with compound for 15 mins followed by A23187 addition measured after 10 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of 5-LOX in human Neutrophil preincubated with compound for 15 mins followed by A23187 addition measured after 10 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50640307(CHEMBL5566074)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of 5-LOX in human Neutrophil using arachidonic acid as substrate preincubated with compound for 15 mins followed by substrate and A23187 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50640306(CHEMBL5570344)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of 5-LOX in human Neutrophil preincubated with compound for 15 mins followed by A23187 addition measured after 10 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50640307(CHEMBL5566074)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate preincubated with compound for 15 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandPNGBDBM50640306(CHEMBL5570344)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate preincubated with compound for 15 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed