Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50021504
TargetAutotaxin(Human)TBA
LigandPNGBDBM50187693(CHEMBL3186509)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)TBA
LigandPNGBDBM50322727(4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641343(CHEMBL5573885)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant human ATXgamma using LPC16:0 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641343(CHEMBL5573885)
Affinity DataIC50: 384nMAssay Description:Inhibition of recombinant human ATXbeta using LPC16:0 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641343(CHEMBL5573885)
Affinity DataKi:  432nMAssay Description:Non competitive inhibition of human ATXbeta using LPC18:1 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641343(CHEMBL5573885)
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant human ATXbeta using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)TBA
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataEC50:  460nMAssay Description:Inhibition of recombinant human ATXbeta using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641342(CHEMBL5569276)
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant human ATXgamma using LPC16:0 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641342(CHEMBL5569276)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant human ATXbeta using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641342(CHEMBL5569276)
Affinity DataIC50: 880nMAssay Description:Inhibition of recombinant human ATXbeta using LPC16:0 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641343(CHEMBL5573885)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human ATXgamma using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641341(CHEMBL5565841)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human ATXbeta using LPC16:0 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641342(CHEMBL5569276)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of recombinant human ATXgamma using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641341(CHEMBL5565841)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human ATXbeta using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641341(CHEMBL5565841)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human ATXgamma using LPC16:0 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641341(CHEMBL5565841)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human ATXgamma using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641344(CHEMBL5590303)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human ATXbeta using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641344(CHEMBL5590303)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human ATXgamma using LPC16:0 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641345(CHEMBL5555187)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human ATXbeta using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641345(CHEMBL5555187)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human ATXbeta using LPC16:0 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641344(CHEMBL5590303)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human ATXbeta using LPC16:0 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAutotaxin(Human)TBA
LigandPNGBDBM50641344(CHEMBL5590303)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human ATXgamma using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed