Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50021590
LigandPNGBDBM50642262(CHEMBL5572993)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of PDE1C (unknown origin) expressed in Escherichia coli BL21 using [3H]cGMP as substrate incubated for 15 mins by liquid scintillation met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642262(CHEMBL5572993)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of PDE1C (unknown origin) using [3H]-cAMP as substrate incubated for 1 hr by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642262(CHEMBL5572993)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of PDE1B (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642262(CHEMBL5572993)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of PDE1B (unknown origin) using [3H]-cAMP as substrate incubated for 1 hr by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642262(CHEMBL5572993)
Affinity DataIC50: 1nMAssay Description:Inhibition of PDE1A (unknown origin) using [3H]-cAMP as substrate incubated for 1 hr by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642262(CHEMBL5572993)
Affinity DataIC50: 1nMAssay Description:Inhibition of full-length recombinant human PDE1A using [3H]-cGMP as substrate incubated for 10 mins by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642265(CHEMBL5575643)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PDE1C (unknown origin) expressed in Escherichia coli BL21 using [3H]cGMP as substrate incubated for 15 mins by liquid scintillation met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642263(CHEMBL5568686)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PDE1B (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642266(CHEMBL5572409)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of PDE1C (unknown origin) expressed in Escherichia coli BL21 using [3H]cGMP as substrate incubated for 15 mins by liquid scintillation met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642264(CHEMBL5571465)
Affinity DataIC50: 21nMAssay Description:Inhibition of PDE1B (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642268(CHEMBL5573991)
Affinity DataIC50: 26nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642272(CHEMBL5570207)
Affinity DataIC50: 32nMAssay Description:Inhibition of PDE1A3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM289541(8-((1,4-Oxazepan-4-yl)methyl)-6-(4-methoxybenzyl)t...)
Affinity DataIC50: 100nMAssay Description:Inhibition of PDE1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50150119(CHEMBL3769414)
Affinity DataKi:  160nMAssay Description:Binding affinity to PDE4A (unknown origin) using [3H]cAMP as substrate assessed as inhibition constant incubated for 1 hr by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50150119(CHEMBL3769414)
Affinity DataKi:  160nMAssay Description:Binding affinity to PDE4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642269(CHEMBL5566502)
Affinity DataIC50: 573nMAssay Description:Inhibition of PDE1C (unknown origin) using [3H]-cAMP as substrate incubated for 1 hr by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642272(CHEMBL5570207)
Affinity DataIC50: 790nMAssay Description:Inhibition of PDE1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50318493(Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of PDE1C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50150119(CHEMBL3769414)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity to PDE11A (unknown origin) using [3H]cAMP as substrate assessed as inhibition constant incubated for 1 hr by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642264(CHEMBL5571465)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50150119(CHEMBL3769414)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity to PDE10A (unknown origin) using [3H]cAMP as substrate assessed as inhibition constant incubated for 1 hr by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50058210([9-(2-Fluoro-benzyl)-9H-purin-6-yl]-methyl-amine; ...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to PDE4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50318493(Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE1A (unknown origin) using [3H]-cAMP as substrate incubated for 1 hr by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642270(CHEMBL5571580)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PDE1C (unknown origin) using [3H]-cAMP as substrate incubated for 1 hr by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642271(CHEMBL5567267)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PDE1C (unknown origin) using [3H]-cAMP as substrate incubated for 1 hr by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642264(CHEMBL5571465)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642269(CHEMBL5566502)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of PDE1B (unknown origin) using [3H]-cAMP as substrate incubated for 1 hr by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50150119(CHEMBL3769414)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity to PDE8A (unknown origin) using [3H]cAMP as substrate assessed as inhibition constant incubated for 1 hr by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50150119(CHEMBL3769414)
Affinity DataKi:  3.10E+3nMAssay Description:Binding affinity to PDE3B (unknown origin) using [3H]cAMP as substrate assessed as inhibition constant incubated for 1 hrs by surface plasmon resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642269(CHEMBL5566502)
Affinity DataIC50: 4.66E+3nMAssay Description:Inhibition of PDE1A (unknown origin) using [3H]-cAMP as substrate incubated for 1 hr by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50058210([9-(2-Fluoro-benzyl)-9H-purin-6-yl]-methyl-amine; ...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642264(CHEMBL5571465)
Affinity DataIC50: 8.52E+3nMAssay Description:Inhibition of full-length recombinant human PDE2A using [3H]-cGMP as substrate incubated for 10 mins by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50059035(3-Isobutyl-8-methoxymethyl-1-methyl-3,9-dihydro-pu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642264(CHEMBL5571465)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full-length recombinant human PDE8A using [3H]-cAMP as substrate incubated for 10 mins by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642266(CHEMBL5572409)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50540044(CHEMBL4644729)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642266(CHEMBL5572409)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE3A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50540044(CHEMBL4644729)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE3A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642266(CHEMBL5572409)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642262(CHEMBL5572993)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length PDE10AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50540044(CHEMBL4644729)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642262(CHEMBL5572993)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642262(CHEMBL5572993)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50150119(CHEMBL3769414)
Affinity DataKi:  1.70E+4nMAssay Description:Binding affinity to PDE9A (unknown origin) using [3H]cAMP as substrate assessed as inhibition constant incubated for 1 hr by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50150119(CHEMBL3769414)
Affinity DataKi:  1.80E+4nMAssay Description:Binding affinity to PDE2A (unknown origin) using [3H]cAMP as substrate assessed as inhibition constant incubated for 1 hrs by surface plasmon resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642267(CHEMBL5584027)
Affinity DataIC50: 3.17E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50058210([9-(2-Fluoro-benzyl)-9H-purin-6-yl]-methyl-amine; ...)
Affinity DataKi:  3.50E+4nMAssay Description:Binding affinity to PDE3B (unknown origin) using [3H]cAMP as substrate assessed as inhibition constant incubated for 1 hrs by surface plasmon resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50642262(CHEMBL5572993)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PDE3A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50058210([9-(2-Fluoro-benzyl)-9H-purin-6-yl]-methyl-amine; ...)
Affinity DataKi:  1.22E+5nMAssay Description:Inhibition of full-length recombinant human PDE2A using [3H]-cGMP as substrate incubated for 10 mins by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed