Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50021926
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50646232(CHEMBL5594904)
Affinity DataKd:  150nMAssay Description:Binding affinity to STAT3 SH2 domain (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50646232(CHEMBL5594904)
Affinity DataIC50: 190nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50646232(CHEMBL5594904)
Affinity DataIC50: 220nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549118(BDBM50556884 | US11299480, Example 53)
Affinity DataIC50: 270nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50646232(CHEMBL5594904)
Affinity DataIC50: 290nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549118(BDBM50556884 | US11299480, Example 53)
Affinity DataIC50: 350nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549075(BDBM50556877 | US11299480, Example 34)
Affinity DataIC50: 370nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549046(US11299480, Example 102)
Affinity DataIC50: 380nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549075(BDBM50556877 | US11299480, Example 34)
Affinity DataIC50: 500nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549118(BDBM50556884 | US11299480, Example 53)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 (127 to 711 residues) DNA-binding activity transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549046(US11299480, Example 102)
Affinity DataIC50: 660nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549075(BDBM50556877 | US11299480, Example 34)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C468A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50556935(CHEMBL4764925)
Affinity DataIC50: 870nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549118(BDBM50556884 | US11299480, Example 53)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549075(BDBM50556877 | US11299480, Example 34)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50556935(CHEMBL4764925)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549118(BDBM50556884 | US11299480, Example 53)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C542S mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549046(US11299480, Example 102)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50556935(CHEMBL4764925)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549118(BDBM50556884 | US11299480, Example 53)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C468A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549075(BDBM50556877 | US11299480, Example 34)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 (127 to 711 residues) DNA-binding activity transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549046(US11299480, Example 102)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 (127 to 711 residues) DNA-binding activity transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549118(BDBM50556884 | US11299480, Example 53)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C328A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50556935(CHEMBL4764925)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 (127 to 711 residues) DNA-binding activity transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataIC50: 5.30E+3nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549046(US11299480, Example 102)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C542S mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549046(US11299480, Example 102)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C426A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549075(BDBM50556877 | US11299480, Example 34)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C328A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50556935(CHEMBL4764925)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C542S mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549075(BDBM50556877 | US11299480, Example 34)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C542S mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataIC50: 6.80E+3nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50556935(CHEMBL4764925)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C426A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50556935(CHEMBL4764925)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C328A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549075(BDBM50556877 | US11299480, Example 34)
Affinity DataIC50: 8.60E+3nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549046(US11299480, Example 102)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C328A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549118(BDBM50556884 | US11299480, Example 53)
Affinity DataIC50: 9.70E+3nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C426A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C328A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 (127 to 711 residues) DNA-binding activity transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549121(BDBM50556885 | US11299480, Example 133)
Affinity DataIC50: 1.45E+4nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549118(BDBM50556884 | US11299480, Example 53)
Affinity DataIC50: 1.58E+4nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) DNA-binding activity transfected in v-Src transformed mouse NIH3T3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549121(BDBM50556885 | US11299480, Example 133)
Affinity DataIC50: 1.89E+4nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549118(BDBM50556884 | US11299480, Example 53)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C426A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of recombinant wild type tyrosine phosphorylated C-terminal 6His tagged human STAT3 C468A mutant (127 to 711 residues) DNA-binding activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50353441(CHEMBL1829786)
Affinity DataIC50: 2.01E+4nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM549075(BDBM50556877 | US11299480, Example 34)
Affinity DataIC50: 2.03E+4nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50353441(CHEMBL1829786)
Affinity DataIC50: 2.16E+4nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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