Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50021414
LigandPNGBDBM50006932(CHEMBL3237245)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human Keap1 KELCH domain (321 to 609 residues) expressed in Escherichia coli BL21 DE3 pLysS cells/Nrf2 (unknown origin) protein-protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50640392(CHEMBL5556774)
Affinity DataIC50: 26nMAssay Description:Inhibition of human Keap1 KELCH domain (321 to 609 residues) expressed in Escherichia coli BL21 DE3 pLysS cells/Nrf2 (unknown origin) protein-protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50640393(CHEMBL5569878)
Affinity DataKi:  6.15E+3nMAssay Description:Binding affinity to human Keap1-Nrf2 protein-protein interaction assessed as inhibition constant incubated for 60 mins by fluorescent polarization as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50640394(CHEMBL5570318)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of amyloid beta 42 (unknown origin) self aggregation by Thioflavin T-based fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50170723(N',N'''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(im...)
Affinity DataKd: <3.00E+4nMAssay Description:Binding affinity to human Keap1-Nrf2 protein-protein interaction assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed