Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50021596
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant full-length human PDK1 (1 to 436 residues) expressed in baculovirus infected Sf9 insect cells using PDHA1 as substrate incu...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDK1 by ADPGlo Kinase AssayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataEC50: 49nMAssay Description:Inhibition of 6His-tagged full length PDK1 (unknown origin) expressed in Escherichia coli in presence of ATP by ELISA based kinase activity assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of PDK1 (unknown origin) by chemiluminescence based ADPGlo Kinase AssayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant full length human PDK2 (1 to 407 residues) expressed in baculovirus infected Sf9 cells using PDHA1 as substrate incubated f...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of recombinant full-length human PDK1 (1 to 436 residues) expressed in baculovirus infected Sf9 insect cells using PDHA1 as substrate incu...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataIC50: 121nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length PDK3 (1 to 406 residues) expressed in baculovirus infected Sf9 cells using PDHA1 as...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant full length human PDK2 (1 to 407 residues) expressed in baculovirus infected Sf9 cells using PDHA1 as substrate incubated f...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataKd: 148nMAssay Description:Binding affinity to PDK1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataIC50: 459nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length PDK3 (1 to 406 residues) expressed in baculovirus infected Sf9 cells using PDHA1 as...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full length human PDK4 (1 to 411 residues ) expressed in baculovirus infected Sf9 cells using PDHA1 a...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataIC50: 8.67E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full length human PDK4 (1 to 411 residues ) expressed in baculovirus infected Sf9 cells using PDHA1 a...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Chongqing Medical and Pharmaceutical College
Curated by ChEMBL
Affinity DataKd: 8.90E+3nMAssay Description:Binding affinity to PDK1 (unknown origin) assessed as dissociation constant in presence of 5-((4-chlorophenyl)sulfonamido)-N-(2-hydroxyethyl)-2,4-dim...More data for this Ligand-Target Pair
