Compile Data Set for Download or QSAR
Report error Found 69 Enz. Inhib. hit(s) with all data for entry = 50021608
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50199786(CHEMBL3918282)
Affinity DataKi:  0.806nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642529(CHEMBL5566764)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642528(CHEMBL5571978)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642521(CHEMBL5567260)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642516(CHEMBL5566980)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642517(CHEMBL5592085)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50199786(CHEMBL3918282)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]WIN35428 from wild type human DAT expressed in COS-7 cells incubated for 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642520(CHEMBL5595313)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642518(CHEMBL5573195)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642517(CHEMBL5592085)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]WIN35428 from wild type human DAT expressed in COS-7 cells incubated for 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642519(CHEMBL5566574)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642524(CHEMBL5595192)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642517(CHEMBL5592085)
Affinity DataKi:  40nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642540(CHEMBL3084652)
Affinity DataKi:  56nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642514(CHEMBL5569659)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642522(CHEMBL5590215)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642514(CHEMBL5569659)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]WIN35428 from wild type human DAT expressed in COS-7 cells incubated for 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642526(CHEMBL5567487)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642532(CHEMBL5572067)
Affinity DataKi:  92nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642540(CHEMBL3084652)
Affinity DataKi:  96nMAssay Description:Displacement of [3H]WIN35428 from wild type human DAT expressed in COS-7 cells incubated for 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642532(CHEMBL5572067)
Affinity DataKi:  106nMAssay Description:Displacement of [3H]WIN35428 from wild type human DAT expressed in COS-7 cells incubated for 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642538(CHEMBL5571244)
Affinity DataKi:  135nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642532(CHEMBL5572067)
Affinity DataKi:  136nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642514(CHEMBL5569659)
Affinity DataKi:  163nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642523(CHEMBL5571533)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642528(CHEMBL5571978)
Affinity DataKi:  201nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM86207(NSC_446220 | CAS_50-36-2 | COCAINE)
Affinity DataKi:  219nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642527(CHEMBL5583627)
Affinity DataKi:  276nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM86207(NSC_446220 | CAS_50-36-2 | COCAINE)
Affinity DataKi:  287nMAssay Description:Displacement of [3H]WIN35428 from wild type human DAT expressed in COS-7 cells incubated for 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642516(CHEMBL5566980)
Affinity DataKi:  288nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642532(CHEMBL5572067)
Affinity DataKi:  326nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642523(CHEMBL5571533)
Affinity DataKi:  355nMAssay Description:Displacement of [3H]WIN35428 from wild type human DAT expressed in COS-7 cells incubated for 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642518(CHEMBL5573195)
Affinity DataKi:  360nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642525(CHEMBL5575799)
Affinity DataKi:  382nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642515(CHEMBL5574043)
Affinity DataKi:  417nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642520(CHEMBL5595313)
Affinity DataKi:  504nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642536(CHEMBL5576011)
Affinity DataKi:  508nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642530(CHEMBL5569644)
Affinity DataKi:  662nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642534(CHEMBL5563060)
Affinity DataKi:  725nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642536(CHEMBL5576011)
Affinity DataKi:  732nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642526(CHEMBL5567487)
Affinity DataKi:  759nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642530(CHEMBL5569644)
Affinity DataKi:  780nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642529(CHEMBL5566764)
Affinity DataKi:  818nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50199789(CHEMBL3931765)
Affinity DataKi:  917nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642534(CHEMBL5563060)
Affinity DataKi:  923nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642523(CHEMBL5571533)
Affinity DataKi:  949nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50199789(CHEMBL3931765)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [3H]WIN35428 from wild type human DAT expressed in COS-7 cells incubated for 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642539(CHEMBL5569416)
Affinity DataKi:  1.05E+3nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50642524(CHEMBL5595192)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50002316(LARODOPA | SINEMET | 4-(2-Amino-ethyl)-benzene-1,2...)
Affinity DataKi:  1.92E+3nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
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