Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 50021617
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642718(CHEMBL5569901)
Affinity DataKi:  0.00500nMAssay Description:Binding affinity to Hepatitis C virus genotype 1a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642717(Mk-2748 | MK2748)
Affinity DataKi:  0.00900nMAssay Description:Binding affinity to Hepatitis C virus genotype 1a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642717(Mk-2748 | MK2748)
Affinity DataIC50: 0.00900nMAssay Description:Inhibition of Hepatitis C virus genotype 1a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642734(CHEMBL5575722)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642716(CHEMBL5568614)
Affinity DataIC50: 0.0130nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50485494(CHEMBL2063089)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to full length Hepatitis C virus genotype 1b NS4B expressed in Escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642715(CHEMBL3786672)
Affinity DataIC50: 0.0330nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642727(CHEMBL5568760)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity to full length Hepatitis C virus genotype 1b NS4B expressed in Escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM103836(Vaniprevir)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity to Hepatitis C virus genotype 1b NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50573891(Glecaprevir | A-1282576 | A-1282576.0 | A-12825760...)
Affinity DataKi:  0.0530nMAssay Description:Binding affinity to Hepatitis C virus genotype 2a NS5B polymerase assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642719(Sovaprevir | ACH-0141625)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity to Hepatitis C virus genotype 1b NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50573891(Glecaprevir | A-1282576 | A-1282576.0 | A-12825760...)
Affinity DataKi:  0.0630nMAssay Description:Binding affinity to Hepatitis C virus genotype 1b NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50573891(Glecaprevir | A-1282576 | A-1282576.0 | A-12825760...)
Affinity DataKi:  0.0750nMAssay Description:Binding affinity to Hepatitis C virus genotype 1a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642729(Gs-9256)
Affinity DataKi:  0.0890nMAssay Description:Binding affinity to full length Hepatitis C virus genotype 1b NS4B expressed in Escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50573891(Glecaprevir | A-1282576 | A-1282576.0 | A-12825760...)
Affinity DataKi:  0.0920nMAssay Description:Binding affinity to Hepatitis C virus genotype 4a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50573891(Glecaprevir | A-1282576 | A-1282576.0 | A-12825760...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity to Hepatitis C virus genotype 6a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Hepatitis C virus genotype 6 NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Hepatitis C virus genotype 5 NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Hepatitis C virus genotype 4 NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Hepatitis C virus genotype 1a NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642718(CHEMBL5569901)
Affinity DataKi:  0.260nMAssay Description:Binding affinity to Hepatitis C virus genotype 3a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50485494(CHEMBL2063089)
Affinity DataKi:  0.310nMAssay Description:Binding affinity to Hepatitis C virus genotype 3a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642720(CHEMBL5583648)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of Hepatitis C virus genotype 3a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Hepatitis C virus genotype 4a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Hepatitis C virus genotype 6a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Hepatitis C virus genotype 1a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Hepatitis C virus genotype 5a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642716(CHEMBL5568614)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Hepatitis C virus genotype 3a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642732(CHEMBL1779107)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50573891(Glecaprevir | A-1282576 | A-1282576.0 | A-12825760...)
Affinity DataKi:  0.920nMAssay Description:Binding affinity to Hepatitis C virus genotype 4a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50573891(Glecaprevir | A-1282576 | A-1282576.0 | A-12825760...)
Affinity DataKi:  0.960nMAssay Description:Binding affinity to Hepatitis C virus genotype 3a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataKi:  0.970nMAssay Description:Binding affinity to Hepatitis C virus genotype 1b NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50461557(CHEMBL414993)
Affinity DataIC50: 1nMAssay Description:Inhibition of Hepatitis C virus genotype 1a NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)
Affinity DataKi:  1nMAssay Description:Binding affinity to Hepatitis C virus genotype 1a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642717(Mk-2748 | MK2748)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to Hepatitis C virus genotype 3a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642713(Furaprevir | Tg-2349 | TG-2349)
Affinity DataEC50:  1.60nMAssay Description:Inhibition of Hepatitis C virus genotype 3a NS4B expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Hepatitis C virus genotype 2b NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642714(CHEMBL5570439)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM103836(Vaniprevir)
Affinity DataIC50: 3nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Hepatitis C virus genotype 3a NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50573891(Glecaprevir | A-1282576 | A-1282576.0 | A-12825760...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Hepatitis C virus genotype 2b NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50573891(Glecaprevir | A-1282576 | A-1282576.0 | A-12825760...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of Hepatitis C virus genotype 1a NS4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642721(CHEMBL3952146)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of Hepatitis C virus genotype 3a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642715(CHEMBL3786672)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of Hepatitis C virus genotype 3a NS4BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM12311(SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...)
Affinity DataKi:  6nMAssay Description:Binding affinity to Hepatitis C virus genotype 1a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM12311(SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...)
Affinity DataKi:  6nMAssay Description:Binding affinity to Hepatitis C virus genotype 3a NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-structural protein 4b(Hepacivirus hominis)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM12311(SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...)
Affinity DataKi:  6nMAssay Description:Binding affinity to Hepatitis C virus genotype 2b NS4B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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