Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50021619
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM575635(US11464802, Compound 4)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal biotinylated Avi-tagged Cbl-b (36 to 427 residues) (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM585804(US11530229, Compound 19)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal biotinylated Avi-tagged Cbl-b (36 to 427 residues) (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM585844(US11530229, Compound 60)
Affinity DataIC50: 21nMAssay Description:Inhibition of CBL-B (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642756(CHEMBL5562897 | US20250230147, Compound 477)
Affinity DataIC50: 36nMAssay Description:Inhibition of Cbl-b (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642752(CHEMBL5084647)
Affinity DataIC50: 38nMAssay Description:Inhibition of CBL-B (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642757(CHEMBL5592177 | US20250230147, Compound 154)
Affinity DataIC50: 72nMAssay Description:Inhibition of Cbl-b (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642751(CHEMBL5085332)
Affinity DataIC50: 88nMAssay Description:Inhibition of CBL-B (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642750(CHEMBL5088448)
Affinity DataIC50: 92nMAssay Description:Inhibition of CBL-B (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642753(CHEMBL5085779)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal biotinylated Avi-tagged Cbl-b (36 to 427 residues) (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642758(CHEMBL5573247)
Affinity DataIC50: 100nMAssay Description:Inhibition of Cbl-b (unknown origin) using fluorophore-labeled probe by TR-FRET based Cb1-b displacement assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-C(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642756(CHEMBL5562897 | US20250230147, Compound 477)
Affinity DataIC50: 110nMAssay Description:Inhibition of C-Cbl (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-C(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642757(CHEMBL5592177 | US20250230147, Compound 154)
Affinity DataIC50: 220nMAssay Description:Inhibition of C-Cbl (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642749(CHEMBL5092933)
Affinity DataIC50: 230nMAssay Description:Inhibition of CBL-B (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642752(CHEMBL5084647)
Affinity DataIC50: 780nMAssay Description:Inhibition of Cbl-b (unknown origin) by Cellular substrate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM585844(US11530229, Compound 60)
Affinity DataIC50: 790nMAssay Description:Inhibition of Cbl-b (unknown origin) by Cellular substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642751(CHEMBL5085332)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Cbl-b (unknown origin) by Cellular substrate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642745(CHEMBL5583714)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of CBL-B (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642745(CHEMBL5583714)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of CBL-B (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642748(CHEMBL5564717)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CBL-B (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642748(CHEMBL5564717)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to CBL-B (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642747(CHEMBL5583756)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of CBL-B (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642747(CHEMBL5583756)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to CBL-B (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642754(CHEMBL5573796)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cbl-b (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642755(CHEMBL5573855)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cbl-b (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642746(CHEMBL5572279)
Affinity DataIC50: 1.67E+5nMAssay Description:Inhibition of CBL-B (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed