Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50019480
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619553BDBM50619553(CHEMBL5415578)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619556BDBM50619556(CHEMBL5413564)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619552BDBM50619552(CHEMBL5408294)
Affinity DataIC50: 13nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619555BDBM50619555(CHEMBL5402298)
Affinity DataIC50: 49nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619551BDBM50619551(CHEMBL5429450)
Affinity DataIC50: 180nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619561BDBM50619561(CHEMBL5431314)
Affinity DataIC50: 340nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619564BDBM50619564(CHEMBL5408905)
Affinity DataIC50: 410nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619563BDBM50619563(CHEMBL5401101)
Affinity DataIC50: 460nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619559BDBM50619559(CHEMBL5437416)
Affinity DataIC50: 500nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619560BDBM50619560(CHEMBL5428469)
Affinity DataIC50: 520nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619557BDBM50619557(CHEMBL5397857)
Affinity DataIC50: 530nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619532BDBM50619532(CHEMBL5407974)
Affinity DataIC50: 550nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619564BDBM50619564(CHEMBL5408905)
Affinity DataIC50: 550nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619562BDBM50619562(CHEMBL5404413)
Affinity DataIC50: 690nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619533BDBM50619533(CHEMBL5420106)
Affinity DataIC50: 880nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619537BDBM50619537(CHEMBL5407640)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619549BDBM50619549(CHEMBL5433325)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619550BDBM50619550(CHEMBL5413213)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619542BDBM50619542(CHEMBL5421903)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619538BDBM50619538(CHEMBL5400481)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619541BDBM50619541(CHEMBL5400366)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619547BDBM50619547(CHEMBL5439684)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619546BDBM50619546(CHEMBL5440407)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619544BDBM50619544(CHEMBL5432250)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619539BDBM50619539(CHEMBL5403626)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619534BDBM50619534(CHEMBL5403842)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619554BDBM50619554(CHEMBL5413109)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619536BDBM50619536(CHEMBL5429318)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619543BDBM50619543(CHEMBL5399365)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619548BDBM50619548(CHEMBL5401087)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619558BDBM50619558(CHEMBL5406019)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619545BDBM50619545(CHEMBL5407525)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619531BDBM50619531(CHEMBL5438399)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619535BDBM50619535(CHEMBL5434458)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619540BDBM50619540(CHEMBL5423141)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed